Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08767 Cgp-60474 GSE70138 HA1E Human 24h 0.12uM EID0001
Types Number Response transcription factors
Up-regulation 708 IKZF1; THRB; RFX1; MEF2C; CEBPD; AR; SOX3; ZFY; ZNF154; E2F2; PRDM9; NEUROG2; ALX4; CHD2; HES2; MAML3; NFKB2; HDAC9; NEUROD4; ZNF235; ZNF221; HOXB8; ZNF208; ZNF816; ZNF695; DCC; TULP2; TBX5; DOT1L; POU6F2; IKZF2; SCAI; TEF; TCEA2; FOXE3; POU1F1; PAX3; NEUROD2; POU2F3; ESRRB; TULP1; NFIX; SCRT1; SOX5; CARF; HOXD12; PROP1; RFX3; KLF15; ZNF549; BRDT; SRY; TBR1; HOXC5; SP4; ZNF606; PRDM16; SIX3; ONECUT1; FEZF2; PRRX1; ZNF117; OVOL2; SOX1; ZNF749; TP73; ZNF507; ZNF257; NR2E1; GBX1; ZNF550; TBX6; TFDP3; ATF6B; IKZF3; FOXD3; GSC2; FOS; PAX7; ZIC3; NEUROD6; KLF8; RSF1; PRDM14; NR5A1; ZNF557; EP300; ZSCAN2; NACA2; SOX14; ZNF225; CDX4; ZNF343; ZNF132; ZNF287; LBX1; ZNF682; TFAP2B; ZNF814; ZNF345; ZNF180; ZNF391; ATN1; SSBP3; BCL11A; ACTL6B; ZNF442; NEUROG1; GCM2; ZFP2; ZNF222; SSX7; AIRE; LHX3; MAK; POU3F3; ZBTB44; ASCL3; ZNF407; FOXP3; TLX2; ALX3; ZNF780B; POU3F4; NR5A2; VENTX; PAX4; SOX21; ZKSCAN4; HOXB1; ZNF43; HNF4A; ZIC4; FOSL1; ZNF136; ZNF81; ZXDC; ZNF669; PAX1; PRDM2; POU4F3; EMX1; ETV2; ZNF80; MDM2; FOXL1; ZNF471; HESX1; ZNF75D; ZNF214; ZNF484; PRDM12; ZNF10; ZNF528; MAPK8IP1; ZXDB; GBX2; IRF6; PDX1; TUB; MYNN; ZNF440; ZNF674; ASH1L; AFF3; TLX3; ZKSCAN8; ZNF264; FOXB1; DMRT1; RORB; GRIP1; ATOH1; RBPJL; SOX17; ZNF778; HEYL; VGLL1; MYEF2; ESR1; THAP9; NKX6-1; MLLT1; PRDM5; ZNF134; ZNF273; ZSCAN9; ZFPM2; HIPK2; TBL1Y; PPARA; ZNF701; NHLH2; TBX19; ZNF8; ZFHX2; ZNF573; ZNF141; ZNF253; ZNF667; VHL; LZTR1; ZBTB3; AFF2; MYC; TAF4B; ETV3; SPI1; ZNF157; HSF4; NHLH1; NEUROG3; SOX18; ZNF492; BRWD1; HOXC8; CDIP1; CBX8; ZNF254; SOHLH2; ZNF219; THAP10; NR1I3; ZNF215; HIVEP3; HDAC11; BNC1; MSX2; TAF1A; THRA; CBX2; ZNF571; SKIL; UTF1; NR6A1; ZNF362; LMX1B; HIF3A; SOX2; ZNF41; ZNF85; TAF6L; HAND1; POU4F2; FOXH1; SHOX; TAF1; NFATC4; MECP2; ZNF79; CIITA; VSX1; ASCL2; WHSC1L1; ZNF74; SHOX2; ZNF234; FHL5; THAP3; ZNF544; CBX7; CRX; SIX6; SUV39H2; ZNF224; ZNF334; ONECUT2; RARG; LHX6; HIC1; ZNF529; SSX3; EYA3; LDB1; NEUROD1; NKX2-5; ZNF480; TWIST1; FOXJ2; HAND2; ZNF14; PRDM1; ZNF223; PRDM10; ZNF835; ZNF304; CD3D; ZNF174; ZNF493; HOXA3; FOXA1; REL; NKX3-2; DLX6; ZNF155; FOXN1; IRF9; TONSL; ZNF350; ATF7; ZBTB7C; ZFP69B; SALL2; TBX4; TLX1; OVOL1; EGR4; SIX5; MDM4; ZNF771; MAFK; MED31; ZFP37; ZBTB25; ZNF460; ZNF675; FOXA2; ZNF613; ZNF467; ZNF142; POU6F1; ZNF671; HOXD3; GLI2; ZNF44; HNF1A; ARID5A; ZNF197; ETV1; CERS6; ZNF623; ZNF688; SOX30; MED12; LIN28A; KDM4C; ZFHX3; NPAS1; GFI1; ZNF423; HOXA6; SOX15; MBD4; L3MBTL1; ZKSCAN3; ZNF354A; RORC; CBFA2T3; TBX1; ZNF124; MYCL; KAT2B; HNF4G; ST18; MYT1; GCM1; GRHL2; RXRG; MYT1L; GMEB1; ESR2; ELK4; ZIM2; TBX21; TAF7L; HOXB5; RFXAP; CBL; ZNF551; ZSCAN32; NOCT; EN2; ZNF770; RAX; ERBB4; HOXD13; MAP3K10; FOXD2; PPARD; POU5F1B; SNAPC4; E2F4; RORA; CDX1; BARX1; ZNF34; ZNF358; KMT2D; NRL; POU3F2; MED25; ISL1; FOSB; NR2C2; CUX2; IKZF4; ZNF286A; KAT6B; NKX2-8; FOXF2; TSHZ2; GTF2A1; NR4A3; ZNF556; SPDEF; PRDM13; ZNF35; ZBTB6; PRMT2; RING1; ZNF589; MAFF; ZNF654; EBF2; ARHGAP35; PHF1; ZNF250; ATF3; SUPT3H; CRYM; DLX4; PKNOX2; PRDM8; ING4; PHOX2B; CEBPE; SP140L; HOXA2; NR4A2; ZNF415; ZNF787; ZNF324B; FOXF1; HDAC5; WNT4; ZNF93; ZNF500; SOX13; ZNF394; RUNX2; RFX2; TSC22D3; MYF5; ZNF506; ZNF711; EMX2; ZNF112; CALCOCO1; MZF1; SMARCA4; SRCAP; IFNB1; NR0B1; ZNF331; ZNF133; E4F1; BHLHE40; HLX; ZBTB7B; ZNF274; NKRF; PHOX2A; EGR1; SNAI1; ZNF205; EPAS1; NR4A1; NKX2-2; ZNF419; ZNF444; GCFC2; ZNF611; ZNF211; TEAD3; ZNF536; CBX4; EHMT2; ZNF665; MTA2; ZNF135; ZNF239; ETV5; ZBED2; HOXC11; LYL1; ZNF710; NANOG; DLX5; ARNT2; HMGA2; EVX1; ZNF236; TOX; CNOT3; TFAP2A; SMARCB1; CREBL2; MEOX2; LZTS1; NFIC; CIR1; TAF1C; YBX2; ESRRG; IRF8; ZNF764; HEY2; FOXJ1; FOXN2; HNF1B; MNX1; ZNF268; ZNF91; MXI1; ZNF195; INSM1; ZNF107; CBFA2T2; TDRD3; ZBTB39; TAF5L; THRAP3; HMX1; CAMTA2; HHEX; EZH1; FOXC2; IRX4; ARID3B; CSDC2; NR1H4; ZFP30; SIN3B; ZNF552; ARID3A; PGR; CREG1; BARX2; ZBTB48; TFEC; TTF2; MEIS2; STAT2; BRF2; FEV; JUN; TRIB3; AFF4; BCL6; BNC2; SKI; SUPT7L; OLIG2; FOXG1; RCOR3; HIC2; GFI1B; PBXIP1; NAB2; ZNF33B; TAF9B; SP140; POU2F1; GATA1; NR1H2; TRIM22; PPP1R13L; HOXB13; MYF6; ZNF813; ZNF443; BPTF; HIRA; TGFB1; PBX2; KLF11; MYCN; PBX1; HOXD10; ZNF426; SPIB; ZNF580; GATA6; LHX2; RBL2; OSR2; CERS4; RARB; PAX6; CRTC1; TCF21; HEY1; SETDB1; DBP; SOX11; HBP1; WWP1; SSX1; SCMH1; BCL11B; TGS1; BHLHE41; ZNF430; ZNF227; FOXI1; ZNF232; SMAD5; TCEA1; DLX2; ZBTB43; SALL1; ZNF184; JUNB; AEBP1; MEF2D; JUP; CREM; EYA2; STAT4; IFI16; CNOT2; ZKSCAN7; KDM5D; ZNF175; INSR; PNRC1; KLF13; ZFHX4; HLF; CREB5; ZNF768; ZBTB20; MNDA; HMBOX1; ZNF165; HOXD11; ZSCAN31; ZNF329; MECOM; AHR; KLF7; NFE2L3; VPS72; WT1; HSF1; FOXE1; EN1; CALR; HOXC4; FLI1; BCL3; TRIM24; TFDP2; EYA1; TULP3; ARID1A; TCF7; PROX1; BRD4; RLF; JAK2; ZBTB16; TCF4; IRF1; PITX2; NR0B2; ZNF267; NFAT5; ZIC1; HMGA1; E2F5; HOXD1; PLAG1; GATA2; PITX1; HDAC4; NFKBIB; ZNF12; CITED2; CITED1; TRPS1; KLF4; ELF3; PLAGL1; GATA3; ZFP36L2; MSX1; NFE2L2; MYB; TAL1; FOXL2; HOXB2; MAFB; ERG; EHF; RUNX3; TXNIP; EGR3; YBX3; SATB2; PIR; CEBPB; NR1D2; MEIS1; FOXO4; PEG3; MAF; POU2AF1
Down-regulation 183 PAX8; CCNA2; USP22; ERBB2; FHL2; SUV39H1; HNRNPD; XBP1; NUP62; PUF60; SNW1; ATF1; ZNF146; RBM14; EZH2; BASP1; NFIL3; ATF5; UBE2I; SMARCA5; CBX3; HDAC2; SMAD3; SFPQ; ARID4B; FOXJ3; TSC22D2; NPAT; ING2; VEZF1; DEK; GTF2A2; NCOA4; BRD3; MYBL2; SMARCE1; HOXA5; CDK7; CEBPZ; TCERG1; NRIP1; MED1; BRCA1; DDX5; CENPF; NELFB; BLM; ZMYM2; COPS5; REST; DNAJC2; HMGB2; PSMC3IP; TLE1; BAZ1A; CRY1; HOXB7; NCOR2; HSBP1; CNOT1; RNF111; PATZ1; KDM2A; HIF1A; MBD2; TAF9; ITGB3BP; IKBKAP; NPM1; CTBP1; MGA; ZBTB11; PREB; BRD8; BCLAF1; CENPB; EDF1; HOXC6; NR2F2; SMARCC1; KAT7; FOXO3; ELK1; TBL1XR1; TRIM16; ID2; RAN; DNAJC1; NRBF2; BMI1; TBL1X; SOX4; ADNP; YWHAB; ATF6; ATF4; NR2F6; CCDC59; TCF12; CTR9; ENO1; PQBP1; CHD7; MTDH; RCOR1; MEF2A; CBFB; RBBP4; GTF2IRD1; UBE2B; TRIM29; TLE4; TCF20; MED6; CTCF; BATF3; SF1; STAT6; NFE2L1; AFF1; NCOA6; RREB1; AATF; MLX; RBPJ; ZNF410; ZNF266; PHF20; LOXL2; JARID2; BRD7; HOXC10; RNF138; PTTG1; KLF6; PCGF2; WHSC1; CTBP2; MAGED1; FOXC1; HMGB1; CUX1; SSRP1; SMAD4; E2F3; ZNF302; TRIM27; ZBTB18; FOXO1; ASH2L; CHD1; PSPC1; CNOT6; MED13; FLNA; MAX; RUNX1; STAT3; BIRC2; CRK; NFKB1; SMARCA2; ELF5; PURA; KLF5; NFIB; COPS2; SAP30; NCOA1; PBX3; HTATIP2; SIX2; ELF1; TRIP6; WWC1; SIAH2; ZNF131; ZBTB38; SMAD1; DAXX; DNMT3B; ABL1; NR3C1