Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08765 Cgp-60474 GSE70138 HA1E Human 24h 1.11uM EID0001
Types Number Response transcription factors
Up-regulation 641 IKZF1; NFIX; TCEA2; NFKB2; MEF2C; ALX4; RFX1; TULP1; AR; ZNF606; THRB; TBX5; NEUROG2; HOXB8; ZNF544; GBX1; SIX3; NEUROD4; ZNF816; PRDM14; NR2E1; TEF; SOX5; ZNF154; ZKSCAN4; ASH1L; MAML3; ZNF117; FOS; HES2; SSBP3; ZNF778; ZFHX2; BCL11A; PRDM16; THRA; ZNF264; NEUROD6; SCRT1; PROP1; IRF6; CDIP1; ZFY; TBX21; ZNF573; SPI1; ZNF221; E2F2; ZNF345; FOXE3; ZNF208; MAK; HIPK2; PRDM9; POU6F2; CHD2; ZNF235; DCC; TP73; DOT1L; ONECUT1; LHX3; FOXB1; SOX1; HEYL; FOXH1; NPAS1; ATOH1; RBPJL; AIRE; ZNF771; CARF; HIF3A; PDX1; PRDM1; FOXL1; ZNF136; NR5A2; CIITA; ZNF695; SOX21; OVOL2; ZNF467; TFDP3; SOX2; ZNF667; TBX6; ZSCAN2; HOXC5; HIVEP3; ESRRB; FEZF2; ZNF132; PRDM2; SCAI; PRDM5; NEUROD2; TAF1; ATF6B; FOXP3; VENTX; SSX7; ZNF669; ZNF814; PAX7; SOX17; MLLT1; FOXA2; NEUROG1; ESR1; HAND2; TULP2; KLF15; RFX3; ZNF8; HOXB1; ZNF287; NHLH2; PAX3; SOX14; EYA3; NFATC4; ZBTB44; ZFP2; ZNF257; SP4; POU3F4; POU3F3; VGLL1; TAF6L; MAPK8IP1; ZNF343; EMX1; MECP2; ZNF549; ZNF528; FOXD3; CDX4; SOX18; CREG1; EGR1; EP300; NR5A1; ASCL3; TBX10; ZNF442; ZNF43; ALX3; TLX2; ZNF180; ATN1; TSHZ2; TLX3; REL; GSC2; HOXD12; ZNF749; TBX19; CEBPD; ACTL6B; HSF4; SIX5; NKX2-5; LBX1; BRDT; LHX5; NKX3-2; MEIS2; ZFPM2; LMX1B; ZNF362; WHSC1L1; ETV2; MZF1; ZNF75D; HNF1A; SRY; IKZF2; RORC; SHOX2; ZNF350; EHMT2; ZNF471; HESX1; HIC1; NFIC; RAX; TBL1Y; LDB1; CBX2; ZNF671; DLX6; ZNF701; TONSL; SOX3; ZNF550; RFX2; ZNF273; ZNF253; ZKSCAN3; CERS6; NKX6-1; ZNF391; MDM2; FOXF2; GTF2A1; ZNF142; HOXC8; GRIP1; HOXA3; MAP3K10; RSF1; MEOX2; ZSCAN32; THAP3; ZKSCAN8; LZTR1; CBX8; GBX2; ZSCAN9; HLX; ZNF134; JUP; FOXF1; HOXD3; PITX3; TBR1; HDAC11; BARX1; ZNF211; ZNF331; SIX6; ZNF500; CBX4; TFAP2A; POU4F3; NFAT5; SRCAP; AFF3; TWIST1; VSX1; ZBTB3; OVOL1; HNF4A; TBX4; TAF1C; ZNF835; DLX5; SHOX; FOXJ1; ZNF780B; ZNF224; ZNF423; MED12; AFF2; WNT4; ESR2; RNF2; ZNF556; ZNF682; ZNF304; RBFOX2; ZNF205; CD3D; POU1F1; BNC1; ZBTB7B; ZNF484; BRWD1; ISL1; MED25; ETV3; NEUROG3; EBF2; POU3F2; ZBTB7C; POU2F3; NACA2; NKX2-8; MYNN; IKZF3; CDX1; HMGXB3; MAFK; RORB; ZIC4; HDAC9; CBX7; ZNF507; ATF7; L3MBTL1; CRX; ZXDC; KLF8; ZNF407; GCM2; PRDM8; TUB; ONECUT2; PKNOX2; EPAS1; EZH1; NR6A1; ZNF81; CEBPE; ZNF41; ZFP37; NR1I3; NR4A1; ATF3; TCF4; ZNF85; ZNF254; ZIC3; RARG; MDM4; VHL; KDM4C; TOX; SPDEF; ZNF440; NRL; ZNF219; MTA2; GRHL2; ZNF141; ZNF589; PEX14; ZFHX3; LHX6; IFNB1; NHLH1; GLI1; ZNF214; MECOM; ZNF197; FHL5; ZNF334; PRDM10; ZNF223; KMT2D; SALL2; SUPT7L; PAX4; ZNF225; SKIL; BNC2; CAMTA2; ZNF571; UTF1; HOXA6; ZNF586; PRRX1; ZNF551; ZNF787; ZNF529; ZNF674; ZNF426; E4F1; PAX1; SPIB; PRDM12; THAP9; ZNF76; ZNF493; PPARA; ZNF354A; AEBP1; ERBB4; ZNF415; NFX1; FOXN1; ZNF688; TCF21; ZNF215; MYT1L; ZNF286A; NR4A2; ZNF324B; ZNF80; SSX3; RFXAP; GLI2; RORA; BRF2; CLOCK; ZNF10; MYEF2; LZTS1; RING1; HOXB5; ZIM2; NOCT; RBL2; ZNF155; PRMT2; CBFA2T3; ZNF157; ZNF623; MYCBP; TAF7L; TLX1; PPARD; CAMTA1; ZNF124; SAP18; MSX2; NEUROD1; EVX1; E2F4; CALCOCO1; SMARCA4; ZNF460; ZNF44; ZNF112; ZNF783; TRIM33; ARID5A; HMBOX1; GATA1; ASCL2; ZNF710; CUX2; ZNF711; ZNF480; KAT2B; MED31; MXD3; HAND1; ZBTB48; PHOX2A; CBL; ZKSCAN7; KLF7; ZNF93; ZNF222; ZNF675; TFEB; MNX1; ING4; ETV1; HOXD13; ZNF91; ZNF232; ZNF135; ZNF358; ZBTB43; THAP10; BRD2; ZNF552; STAT4; ZNF492; MBD4; EMX2; ZNF234; ZNF557; ELK4; HEY1; ZNF174; DMRT1; ESRRG; CREBL2; SKI; ZFP69B; CNOT3; TGFB1; TAF4B; FOXC2; SMARCB1; ZNF74; THRAP3; SUPT3H; POU4F2; VPS72; CALR; AES; ZNF195; EYA1; ZNF3; KLF13; TCF7L2; ZSCAN31; SNAI1; TAF12; CRTC1; MSX1; ARNT2; HOXA2; HNF4G; ZNF444; EN2; SOX15; SLC2A4RG; TRIB3; LIN28A; ZNF665; BCL6; DBP; FOXJ2; CIR1; HDAC5; ZNF430; GFI1B; TBX1; ZNF14; POU2F1; KDM5C; STAT2; TDP2; PHOX2B; ZNF33B; SETDB1; FOXN2; ZNF12; ZNF107; IRF8; PAX6; GFI1; ZNF611; TCEB2; TXNIP; SP140; MEIS1; NR1H2; ZNF532; NR1H3; GLI3; ST18; LHX2; TDRD3; LITAF; BRD4; BCL3; NR4A3; SREBF2; HBP1; TOX4; CCNT1; FOXA1; TEAD3; ARID3B; MKL2; ZFP30; ZNF175; YBX2; RHOA; PBX1; PIAS1; ETV5; MYRF; GON4L; SOX13; MYT1; CNOT2; ZFHX4; CDX2; ZNF184; PEG3; ETV7; ARRB1; TRIM25; ZBED2; ZNF329; SMAD5; TFDP2; IRF1; POLR3C; TGIF2; PIAS3; BACH2; TCEA1; MXI1; NANOG; HOXD10; SOHLH2; NR2F1; PITX1; MYCL; MEF2D; ARID1A; HLF; NR0B2; ZNF536; TRIM24; ZNF268; ZNF394; ZKSCAN1; TULP3; HOXB13; FOXG1; ZBTB20; EYA2; INSM1; TOPORS; JAK2; HOXD1; NR1H4; NFE2L3; E2F5; ZFP36L2; SOX11; BAZ2A; SP140L; ZNF267; PBXIP1; MYCN; IL16; KDM5D; NR0B1; ZIC1; CREM; TRIM22; NFKBIB; NKX2-2; ZNF652; GATA2; PLAGL1; ZNF83; HMGA1; EGR2; CTNNB1; FOXO4; NR1D2; HEY2; GATA6; CRYM; HHEX; OSR2; KLF9; CREB1; TSC22D1; ELF3; MAF; WT1; RUNX3; LEF1; POU2AF1; TRPS1; MNDA; BHLHE41; TBX2
Down-regulation 195 FHL2; USP22; XBP1; CCNA2; PAX8; HDAC2; ECD; PUF60; HNRNPD; FOSL1; SUV39H1; NFKBIA; RBM14; SNW1; TP53; NFIL3; HOXA10; NUP62; ATF1; ZNF146; HOXA5; SCAND1; SFPQ; BRD3; UBE2I; VEZF1; NCOA4; SUZ12; MED1; CRY1; TBL1XR1; RAN; CCNC; BRCA1; BLM; PPRC1; EED; BAZ1A; CENPF; FOXO3; PHF20; HOXC6; SMAD3; HIF1A; DDX5; NPAT; BCLAF1; NRIP1; MYBL2; NPM1; FOXJ3; RBM39; AATF; BASP1; HMGB2; TSC22D2; TCERG1; YWHAB; PATZ1; MYC; GATAD2A; TBP; CDK7; AFF1; NCOA6; ARID4B; TBPL1; CBX3; BMI1; DEK; CCDC59; NELFB; CTR9; ZBTB11; SF1; DNAJC2; PQBP1; ADNP; NCOR2; MED6; BRD8; NRBF2; ZNF217; ZMYM2; KDM2A; SMARCE1; PCGF2; BRIP1; KAT8; RNF138; PSMC3IP; HOXC10; BIRC2; KAT7; MTDH; ID2; KLF6; SMAD4; SMARCA5; ADNP2; ANKRD1; TLE1; ENO1; TRIM32; CHD1; MED27; NR2F6; HSBP1; ING2; TRIM29; CIZ1; CNOT6; MBD2; REST; ZBTB18; SMARCC1; CEBPZ; MAGED1; BCOR; WHSC1; TAF7; ITGB3BP; RB1; RFC1; TAF9; MAZ; RBL1; RAD21; ILF2; PRPF6; HOXA11; SMARCA2; UBE2B; CNOT1; FOXK2; ELK1; SSRP1; HSF2; AGO2; HOXB7; ASXL1; ATF4; JUND; ZNF672; SPEN; TRIM16; CREB3L1; TRIP6; ZNF410; ZBTB24; TRIM28; BATF3; BTG1; RBBP4; STAT3; EDF1; MYBL1; PTTG1; BHLHE40; FOXM1; GTF2IRD1; MAX; MED13; PBX3; HMGB1; TFAM; TEAD4; DNMT3B; RARA; CEBPB; RREB1; SAP30; ELF1; RBBP8; REPIN1; RNF6; TBL1X; SIM2; DNAJC1; NKX3-1; SIAH2; DAXX; TBX3; MNAT1; PAWR; ZNF131; CRK; FOXC1; LMCD1; SIX1; KLF10; MYB; ABL1; TOX3; CITED2