Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08764 Cgp-60474 GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 615 NFKB2; MEF2C; SIX3; PRDM14; ALX4; ZNF154; RFX1; NFIX; NEUROD4; HOXB8; TULP1; FOS; CEBPD; HSF4; NEUROG2; OVOL2; HEYL; FOXE3; IKZF1; SSBP3; HES2; AIRE; PROP1; FOXJ1; SOX3; SOX21; ZNF816; FOXH1; HOXB1; MAK; TBX6; ESRRB; RBPJL; REL; TAF1; AR; THRB; MAP3K10; PRDM9; TBX5; ZNF778; TCEA1; HOXB5; POU6F2; MAML3; ZNF544; CDX4; ZNF264; SPI1; ZNF117; NEUROD2; SOX2; GBX1; TFDP3; LDB1; BCL11A; SCAI; ASCL3; VENTX; POU3F3; HDAC9; ZFHX2; SCRT1; ZNF224; FOXL1; TEF; ASH1L; HIF3A; SRY; ZNF669; ZNF467; THRA; NFATC4; NHLH2; ZKSCAN4; BARX1; TP73; VGLL1; ZNF667; ZNF695; KLF15; ZNF221; ATN1; PRDM16; ZNF665; TWIST1; ALX3; TBX10; TULP2; NR5A2; ZNF771; RFX3; ZNF550; ATF6B; ZNF208; CARF; BRDT; ZNF606; ZNF343; MED25; ZXDC; TCEA2; PDX1; DCC; ZFY; FOXP3; ZNF235; ZKSCAN3; PAX7; ZSCAN2; ZSCAN9; TCF21; VSX1; NEUROG1; LHX3; SUPT3H; CHD2; SOX1; ZNF257; TAF6L; TSHZ2; TUB; ATOH1; NR5A1; CBX8; ZFP2; EHMT2; NOCT; HOXD12; MAPK8IP1; SRCAP; RAX; SSX7; RARG; SOX14; ZNF611; ZNF287; RING1; ZBTB7C; DOT1L; IKZF2; IKZF4; EGR1; E2F2; FEZF2; ZNF232; HOXC8; ONECUT1; KDM4C; LZTR1; GRIP1; MECP2; ZNF440; ZNF124; PAX1; HESX1; HMGA2; NKX3-2; POU4F3; HOXA3; ZNF136; ZNF44; CDIP1; ETV3; TBL1Y; EMX1; ZNF253; KLF8; ZBTB44; FOXA2; ZNF273; ETV2; DLX6; FHL5; FOXF1; ZIC3; NKX6-1; EP300; ZNF197; HOXC5; ETV1; FOXB1; TBX19; CBX2; PRDM12; ZNF529; FOXD3; ZNF688; ZNF573; NR6A1; PRDM1; NHLH1; ZNF528; TFDP2; HIPK2; UTF1; ZNF549; ZNF749; ZNF43; IRF6; MEIS2; CRX; HAND2; LHX5; LIN28A; GLI1; MYRF; L3MBTL1; ACTL6B; SHOX; NACA2; ZNF345; ZNF142; ERBB4; ZNF682; NEUROG3; POU2F3; KAT2B; YY1; SMARCB1; ZNF471; CD3D; HLX; ZNF219; ZIC4; GBX2; ZNF556; ZNF415; SOX18; WHSC1L1; NEUROD6; SP4; PAX3; ZNF814; ONECUT2; ZNF391; TLX2; MXI1; ZNF362; HOXD3; SOX17; ESR2; ATF7; ST18; ZNF701; ZNF134; ESR1; CBX7; TFAP4; ZBTB7B; HDAC11; LBX1; CREBL2; PAX2; HIC1; SALL2; RORC; TLX1; PITX3; ZNF211; TOX; BNC1; ZNF132; NKX2-8; AFF3; RORB; GSC2; ZNF442; SSX3; ZNF215; MZF1; CALCOCO1; ZNF93; HMX1; TBR1; TLX3; ZBTB32; E2F4; ZNF536; MLLT1; PRDM5; ZNF710; POU3F4; ZNF835; ZNF85; ZXDB; MYCBP; POU1F1; GFI1B; ZFPM2; CDX1; ZNF304; GLI2; ZNF8; TONSL; FOXF2; LMX1B; ARID3B; GCM2; ZNF331; MAFK; HNF4A; E2F5; RFX2; EPAS1; ZNF74; MDM2; FOXN1; ZNF507; ZNF484; AFF2; TFAP2B; KLF7; CBFA2T3; NR4A2; ZNF500; RNF2; PEG3; ZNF91; FOSB; ZNF551; TCF4; ZNF75D; KAT2A; IKZF3; CIITA; ZBTB48; SIX5; ZNF180; ZNF423; HIVEP3; HAND1; OVOL1; TBX21; ISL1; ZNF214; CAMTA2; EVX1; TGS1; ARHGAP35; BNC2; PRDM2; SPDEF; MYNN; NKX2-5; PRDM8; SHOX2; MYCN; NPAS1; ZNF671; SOX5; NR2E1; ZNF430; EBF2; HDAC5; ZNF80; ZNF81; ZNF623; IRF1; ZNF141; ZNF10; ZKSCAN8; MTA2; PAX4; HIC2; ZBED2; ZIM2; NFIC; ZNF589; RSF1; SUPT7L; ZNF358; HOXA6; POU5F1B; MED12; DLX5; ZNF41; ZNF174; ZNF407; VHL; CEBPE; TERF1; TEAD3; NR1I3; ZNF426; ZNF135; CNOT3; PHF1; MYCL; PBX2; TFAP2A; PRDM10; ZNF157; RFXAP; LITAF; ZNF780B; TBX4; NR1H2; NR4A3; TAF7L; GRHL2; MSX2; ZNF419; HNF4G; KMT2D; THAP9; GFI1; FOXJ2; ZNF155; ZNF674; GATA1; TAF4B; IFNB1; SIX6; TBX1; ZNF286A; ZNF350; WNT4; ZNF254; ZNF493; ZFHX3; PPARD; ZNF557; ZNF250; LHX6; PHOX2A; PITX1; HNF1A; RUNX2; ING4; ZBTB3; ZIC1; ZNF654; THRAP3; MYEF2; PFDN5; TAF1C; ZNF492; ZNF329; ZFP37; ZNF444; AES; PRRX1; EMX2; CSDC2; ZNF764; ZNF225; NR1H4; VPS72; CUX2; MXD3; ASCL2; PPARA; SOX13; CREG1; CDX2; GLI3; ARID5A; LHX2; NANOG; FUBP1; LYL1; GCM1; TAF6; PLAGL1; MNX1; TFEB; HNF1B; CRTC1; HOXA2; ZNF222; HOXB6; JUP; PBX1; ZFP69B; SMAD6; ZSCAN32; ZNF354A; ZNF711; ARNT2; ZNF79; SUPT5H; PHOX2B; ZSCAN18; TULP3; NEUROD1; HOXD1; KLF13; ZNF532; MEIS1; ZFHX4; BCL3; ZNF562; BARX2; TRIB3; COPS5; ATF3; SIM1; PAX6; TGFB1; POU4F2; INSR; MDM4; ZNF675; STAT2; HMBOX1; CREM; EZH1; SUPT6H; ZNF35; ZNF586; SCMH1; NR4A1; ZNF160; ARID3A; RBFOX2; ZNF205; KLF1; CALR; SOHLH2; HMGB3; FOXA1; ZNF334; ZNF107; TAL1; ZNF223; NR0B2; ZNF692; INSM1; SKIL; DBP; HIRA; KLF3; TRPS1; YEATS2; SOX11; KDM5D; BHLHE41; ESRRG; FOXI1; ZNF721; TDP2; CBX4; MECOM; SAP18; ZNF112; AEBP1; ZFP36L2; TCF7; ZKSCAN1; MEOX2; HOXB2; ZNF184; HSF1; NFAT5; NFE2L3; ZNF552; TCF7L2; CNBP; IRF8; CREB5; NCOA2; HEY1; CERS6; MYT1L; PLAG1; HDGF; ZNF239; ZNF652; LEF1; SP140L; NKX2-2; ZNF195; MITF; ZSCAN31; BRD4; HHEX; MNDA; EYA1; EHF; TRIM22; KLF11; NR1I2; ELF3; OSR2; EGR2; FOXL2; SNAI2; ETV5; ZNF165; NR1D2; HMGA1; PBXIP1; SSX1; HEY2; ZNF580; NR2F1; SMARCA1; HOXB13; GATA6; TFEC; HLF; DACH1; YBX3; STAT4; KLF5; CBX6; FOXO4; NR0B1; ID3; AHR; WT1; GATA2; POU2AF1; ID1
Down-regulation 199 FHL2; CCNA2; XBP1; ECD; USP22; NFKBIA; ERBB2; UBE2I; FOSL1; FOXJ3; PUF60; ATF1; SUV39H1; ARID5B; HNRNPD; RBM14; HDAC2; NPAT; PAX8; HOXA10; SNW1; HOXA5; SCAND1; NUP62; NRIP1; TP53; NCOA4; CCDC59; FOXO3; EZH2; DDX54; MED1; CDK7; NELFB; NFIL3; ZNF146; BLM; SFPQ; RAN; NCOA6; PHF20; MYBL2; MYC; CENPF; HOXC6; GTF2A2; SOX4; CRY1; YWHAB; AFF1; REST; BASP1; CNOT1; BHLHE40; BRD3; ARID4B; SMARCA5; BAZ1B; KAT7; BCLAF1; HIF1A; ADNP; ASXL1; MAGED1; ZNF266; TCERG1; CBX3; BRCA1; TRIM32; ZBTB11; CDK2; RNF111; HSF2; KAT5; SAP130; BAZ1A; VEZF1; DEK; NCOR2; SMAD3; SMARCE1; CTR9; MED17; PATZ1; DNAJC2; KDM2A; CEBPZ; SMARCA2; RBL1; ANKRD1; SMARCC1; NRBF2; NR2F2; ILF2; BTG1; ZBTB1; BRIP1; PSMC3IP; HOXC10; BRD8; TCF25; ZMYM2; TBL1XR1; SETD2; SF1; CCNC; NPM1; TSC22D2; GTF2IRD1; ING2; HMGB2; DDX5; ZBTB18; GATAD2A; PREB; MAX; EDF1; PCGF2; TAF7; MMS19; PRPF6; TLE1; TRIM28; ZNF410; MBD2; SUB1; BMI1; HSBP1; RNF6; TFAM; ENO1; RFC1; ID2; MED13; LPIN2; CBFB; TAF9; NFKB1; JARID2; HOXA11; MED27; FOSL2; ELF1; KLF10; ZBTB24; KLF6; TBL1X; ZNF302; UBE2B; RERE; RREB1; BRD7; FOXK2; PLAGL2; ZNF217; ELK3; FOXC1; YAF2; PQBP1; RFX5; ELF5; FLNA; RARA; CTBP2; TRIM16; IRF7; MED6; CHD8; ATF4; VGLL4; KLF2; STAT1; HMGB1; CITED1; NKX3-1; PTTG1; BIRC2; SP3; STAT6; RBBP4; PSPC1; SP110; TRIM29; MAFB; DAXX; MLXIP; TCF12; SIAH2; NFIB; SERTAD2; NFE2L1; THAP11; FOXO1; DNMT3B; STAT3; TP63; TSC22D1; NR3C1; ABL1