Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08763 Cgp-60474 GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 676 NFIX; ALX4; THRB; RFX1; ZNF154; ZNF544; NEUROD2; TCEA2; ZNF235; FOXE3; CEBPD; NEUROD4; IKZF1; SIX3; BCL11A; CHD2; ZNF778; AR; ZNF43; PRDM9; TAF6L; THRA; PRDM14; NFATC4; ZNF117; MAML3; TP73; HOXB8; DOT1L; ZNF345; KLF15; ZNF573; ZNF606; E2F2; NEUROD6; LHX3; PROP1; ZKSCAN4; TBX5; NEUROG2; IRF6; ZNF75D; HSF4; MAK; FEZF2; ONECUT1; PRDM2; FOXH1; LZTR1; SOX21; ZNF257; SOX1; ZNF85; SSBP3; ZNF816; ZNF589; POU6F2; ZNF142; SOX3; PAX1; NFKB2; TULP1; ESRRB; RBPJL; SCAI; DCC; AIRE; SCRT1; ZNF771; CBX8; HOXC5; BARX1; ZNF682; CDIP1; ZBTB44; SPI1; ACTL6B; TEF; SOX18; ASCL3; ASH1L; NR5A2; ZNF549; ZNF695; NKX2-5; ZSCAN9; NR5A1; HES2; NHLH2; CDX4; SSX7; SRY; PDX1; ZNF343; NKX3-2; ZNF550; ZKSCAN3; ZNF221; ST18; EMX1; ZNF814; RFX3; LDB1; MEIS2; GBX1; PAX7; ZNF180; CBX2; BRWD1; PRDM10; ZIC3; TBL1Y; ZNF273; SOX14; ZNF136; ZNF208; VENTX; RING1; TLX3; ZNF287; NR2E1; ZNF141; ZFHX2; E2F4; RORB; PRDM12; ZNF749; SOX2; ZFY; ZNF442; ATOH1; TRIB3; HEYL; GRIP1; ATF6B; TFDP3; ZIC4; ZNF331; IKZF2; MED25; FOXF2; ZNF667; HDAC5; HOXA3; KLF8; VGLL1; TULP2; ZNF253; LBX1; ZNF507; TBX6; ZNF415; HOXD12; TBR1; REL; SP4; E4F1; POU2F3; SUPT7L; SOX5; ZNF500; ZNF10; ZNF665; ZNF529; CD3D; ZFP69B; ZFP2; ZNF362; ZFPM2; JUP; FOXA2; ZNF132; HOXB1; AFF2; ZNF350; POU3F3; PRDM16; ZNF93; ZNF688; ZNF215; POU4F3; ZNF701; ATN1; ZNF254; FOXD3; MAPK8IP1; SNAPC4; HIF3A; SALL2; PEX14; CRX; ZNF232; TUB; TBX4; NEUROG1; MEF2C; ALX3; HLX; ZNF471; ETV3; POU1F1; ZNF74; ERBB4; ZBTB3; SIX6; ZNF675; PAX3; TAF1C; ZNF225; MZF1; LIN28A; ZNF224; CBX4; SOX13; PITX3; FOXB1; ETV2; NHLH1; OVOL2; ZNF440; PAX4; NEUROD1; TAF4B; CARF; WHSC1L1; GSC2; RORC; HMGXB3; GBX2; ZNF391; TBX21; ZNF304; ZNF669; ELK4; ZNF611; ZNF423; MAP3K10; ZXDC; ZNF81; ZNF214; CAMTA2; NR1I3; ZNF44; FOXL1; IKZF3; GCM2; SETDB1; HOXD13; ZBTB48; SUPT3H; ZNF407; ZNF467; BNC1; CDX1; FOXP3; MBD4; MYNN; ZKSCAN8; MLLT1; FOXN1; ESRRG; ZNF135; ZNF219; ZNF174; ZNF41; NPAS1; TFAP2A; THAP10; PAX6; NR6A1; ZNF711; FOXJ1; CBFA2T3; PAXBP1; ZNF274; HAND2; POU4F2; HESX1; ZNF480; ZNF780B; PRDM13; POU3F4; EHMT2; CIITA; TFAP4; ZNF211; TBX1; SHOX2; SHOX; THAP9; MYCL; CUX2; ING4; ZNF80; ZNF671; HNF4A; PKNOX2; ZNF623; IKZF4; ZNF334; VHL; ZXDB; TCF21; SPDEF; OVOL1; NEUROG3; ZNF674; ZNF157; HIC1; RAX; ZNF835; MECP2; ZNF124; TONSL; AFF3; SMARCB1; ZNF710; HDAC9; UTF1; GFI1B; HOXB5; SRCAP; HEY1; TLX2; SOX17; ARID5A; RSF1; ESR1; ZNF91; ZNF8; POU6F1; ZNF239; L3MBTL1; NR1H4; ZBTB7C; ZSCAN2; HNF1A; POU5F1B; HIPK2; SPIB; VSX1; EYA3; NR4A2; TRPS1; ZIM2; NKX6-1; ZSCAN32; NRL; NR4A1; TOX; RFXAP; MYEF2; ARNT2; PRDM5; THAP3; HOXD3; ZNF112; HINFP; ZNF264; PPARA; ZBTB17; LYL1; ZBED2; ATF7; ZBTB7B; KDM4C; TULP3; ZFHX3; ZNF223; PRRX1; EP300; CALCOCO1; VAX2; TAF1A; HOXD9; NACA2; ZNF134; HMBOX1; ZNF551; HIVEP3; TSHZ2; ZNF556; GRHL2; TWIST1; ARID3B; ZNF34; ZNF155; RARG; ZNF354A; ASCL2; TAF1; ZNF250; HHEX; KAT2A; HMX1; CAMTA1; ZNF692; TBX10; CBX7; BRDT; ZFP37; MYT1L; NAB2; SKIL; HNF4G; NR0B2; NR2C2; FOXF1; TBX19; ZNF787; FHL5; PEG3; MNX1; CREG1; ESR2; ZNF358; DLX6; EPAS1; VPS72; ZNF430; ZNF444; NANOG; NOCT; ZNF557; ZNF33B; FOXI1; FUBP1; SALL1; MSX2; ZNF234; MYF5; NR4A3; ZNF195; TEAD3; CEBPE; PFDN5; MYT1; HIC2; MED12; ZNF484; ZNF177; MED31; SSX3; ZNF3; ZNF324; CBL; ZNF492; ZNF426; HDAC11; ZNF528; STAT4; SIX5; LHX6; JUN; IRF3; NKX2-2; MTA2; PRDM1; HOXB2; AEBP1; TAF5L; AES; TLX1; ZNF571; RFX2; TTF2; CNOT3; ISL1; TDP2; FOXA1; ZBTB20; RXRG; EZH1; NR1H2; TGIF2; MDM4; ZNF613; GFI1; WNT4; PBX2; ZNF536; RORA; KLF7; ZNF286A; CSDC2; HIRA; DLX5; EN2; SOX15; ARID3A; ARL2BP; ZNF586; PBXIP1; BRF2; SOHLH2; INSR; NR0B1; KAT2B; CRTC1; GATA1; LHX2; RBFOX2; HNF1B; ZNF493; NR1H3; TCEA1; HOXA2; ZNF562; CREM; KLF3; CERS4; POU3F2; ZNF770; HOXD11; NR2C1; HOXC11; ZNF329; IRF8; TGFB1; OSR2; MDM2; ZNF335; GLI2; ZNF419; HBP1; ONECUT2; HOXD10; PAX9; SOX11; NR2F1; GCM1; ZSCAN18; HLF; ZNF337; ZNF268; IRF9; CDX2; DLX2; TCF4; ZNF35; EVX1; PBX1; MYRF; ZNF83; NFE2L2; MEOX2; ZNF133; ZKSCAN7; GCFC2; MECOM; EGR1; EN1; CBFA2T2; ZNF432; HEY2; DLX4; E2F5; INSM1; JAK2; SIN3B; ZIC1; ETV6; CNOT2; HAND1; TCF7L2; ZNF654; ZBTB6; STAT2; GON4L; CEBPA; OLIG2; SKI; HOXD1; ZNF580; PITX1; HOXC4; TCF7L1; THAP7; LITAF; ZSCAN31; TFEB; HMGA2; ATF3; ZNF107; WT1; PIAS4; FOXG1; KLF1; MED14; CERS6; MEIS1; WDR77; TDRD3; NR1I2; CCNT1; POU2F1; ZNF248; ZNF205; CRYM; CIR1; BNC2; POLR3C; ZNF165; MXI1; BACH2; BANP; HSF1; YBX3; ZBED1; CALR; ZFP36L2; ZNF721; EMX2; BCL6; KLF11; EYA1; FOSB; SUMO1; HOXB13; TFDP2; NFIC; ZHX2; DBP; ARID1A; PHOX2B; HDGF; ZNF532; ZNF160; KDM5D; SP140L; CREBL2; PNRC1; TRIM24; CTNNB1; TGIF1; RBL2; HDAC4; EHF; HMGA1; MYCN; IRF1; GATA6; SLC2A4RG; BAZ2A; TCF7; YAP1; CSDE1; ZMYND8; NFE2L3; HOXB6; TLE2; NFE2; KLF13; ZBTB16; SSBP2; CREB1; DACH1; BHLHE41; BRD4; FOXL2; SATB2; CEBPB; GATA2; PLAGL1; ID4; CBX6; WWTR1; ID3; ZFP36L1; PAX5; MNDA; NCOA3; CITED2; TRIM22; ID1; TSC22D1
Down-regulation 180 FHL2; TP53; CCNA2; ERBB2; PUF60; NFKBIA; ECD; USP22; NUP62; HNRNPD; ATF1; XBP1; NCOA4; SNW1; NRIP1; NFIL3; FOXO3; SUV39H1; HOXA5; CTR9; RBM14; AFF1; HDAC2; ZNF146; MED1; CBX3; MYC; TBP; ATF6; SFPQ; KAT7; TSC22D2; BRD3; BAZ1B; MAGED1; VEZF1; HOXA10; NCOR2; REST; ZFP64; UBE2I; SMARCE1; SMARCA5; NCOA6; CRY1; BAZ1A; GTF2A2; NRBF2; FOSL1; FOXJ3; BMI1; KDM2A; HOXC6; BHLHE40; SMAD2; NELFB; NPAT; CBFB; SCAND1; DDX5; PPRC1; SMARCC1; HIF1A; ING2; RBBP4; YWHAB; SMAD3; CENPF; HSBP1; ZBTB38; RAN; SOX4; ZMYM2; BCLAF1; TCERG1; WHSC1; PQBP1; NPM1; DR1; BIRC2; ZBTB11; SF1; RUNX1; ITGB3BP; DNAJC2; PHF20; ENO1; RNF4; DPF2; CNOT1; TAF10; RNF6; EDF1; HOXB7; CCNC; NFE2L1; ZNF672; BCL10; BLM; TRIM16; RBL1; COPS5; BRCA1; ZBTB1; IRF7; JARID2; SETD2; PATZ1; BRD8; MBD2; CCDC59; HLTF; MAX; PIAS2; BATF3; DNAJC1; TSG101; ASH2L; SUB1; ZBTB18; RNF111; TRRAP; BASP1; MED6; TRIM32; NR2F2; GATAD2A; ELF1; ATF4; HOXC10; PTTG1; HTATIP2; ZMIZ1; HMGB2; MEF2A; ID2; RBBP8; LPIN2; TRIM28; KLF10; SMAD7; SMARCA2; TLE1; DEK; TRIM29; PCGF2; TFAM; FOXC1; GTF2IRD1; KLF2; ELK3; NONO; ASXL1; HOXA1; MNAT1; NR1D2; PDLIM1; TCF12; PURA; ELF5; ZNF217; STAT3; SERTAD2; ZEB2; SAP30; SP110; HMGN3; FLNA; TBL1X; KLF6; TRIP6; THAP11; SIX1; BBX; NKX3-1; BTG1; REPIN1; PTRF; STAT5B; CRK