Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08758 Nvp-aew541 GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 81 MEF2C; TCF4; ZNF589; MTF2; BARX2; YBX2; PRRX1; FOXN3; HDAC6; NFATC1; CDIP1; ST18; ZBTB38; HLF; USF2; NR2E1; HR; PGR; IRF5; FLI1; TOB1; TULP4; FOXA2; MYF6; RCOR1; TAF9B; TWIST1; NKX2-2; IRF8; NFIB; FOXE1; KLF5; KLF9; SIM2; ZNF165; KLF4; ZKSCAN1; SMAD2; NR3C2; MED23; TOX; ZNF430; UBE2B; ZBED1; ZNF189; PBX1; PHF20; INSR; SOX9; PLAGL1; ZNF415; NR1D2; BHLHE41; CTBP2; ZFPM2; GRHL2; HIPK3; HEY2; CUX2; INSM1; ZBTB18; TSC22D1; BCL6; ASCL1; CBFA2T3; NKX2-1; ZEB2; MYB; TXNIP; TFEC; PTRF; ETS2; TBX3; ZFP36L2; KLF6; FOXG1; TRPS1; SMAD1; HOXC6; AHR; DACH1
Down-regulation 52 NRIP1; FOSB; NKX3-1; ARID5A; RERE; LITAF; SMAD7; ZNF3; TRIM33; CHD7; ZNF593; CCDC59; CDK8; BATF3; ZNF562; CIZ1; BCL3; HIPK1; KLF7; TCF21; SSBP3; CD3D; AGO2; ABL1; MDM2; TAF10; HOXB6; EYA1; KAT2B; ARID1A; DDIT3; NR2F2; JARID2; RBBP8; CALR; SERTAD2; SLC2A4RG; ZFP36L1; SIX1; RBPJ; RUNX3; EYA2; KDM5D; BACH2; ZNF22; WWTR1; YBX3; SMARCA1; HOXB2; TBL1X; WT1; TBX2