Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08757 Nvp-aew541 GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 98 CEBPD; TCEA2; TDRD3; ZNF227; ZKSCAN4; TSC22D3; ZNF529; MBD4; EHMT2; PFDN5; ZSCAN16; SREBF2; ZNF329; ZNF675; BRIP1; CARF; TCF25; PRDM10; ZNF254; ING4; SCAI; ZBTB3; ZNF225; SAP18; SOX3; PQBP1; PNRC1; ZNF141; ZNF224; PHIP; SOX12; CREBL2; HDAC9; NHLH2; CAMTA1; YBX3; ZNF223; TSC22D1; TCF7L2; ETV1; MYBL1; E2F8; BCL6; DDX17; TRIB3; HMGB3; ZNF112; SAP30; TOB1; NR0B1; HEY2; PIAS4; SREBF1; NONO; HTATIP2; ING2; ZNF516; NR1H4; ID2; ZNF248; OSR2; ARNT2; BCL11A; NR4A2; PCGF2; PBX1; EMX2; HMGA1; MED23; INSM1; KLF4; CITED2; HDAC4; ZFP36L2; IFI16; MXI1; INSR; ZHX2; APEX1; TFEC; TFAP2C; OLIG2; NPAS2; TCF7; CREM; SOX11; FOXO4; ESR1; CTBP2; WT1; ZNF91; SATB2; TXNIP; DACH1; SOX9; HMG20B; BHLHE41; HOXC6
Down-regulation 59 NFKBIA; MYCBP; USP16; RELB; TCF4; XBP1; MYC; KLF7; BCL10; IRF1; KDM2A; GLI2; TRIP4; PTRF; STAT5A; BATF3; PLAGL2; SFPQ; PRDM1; PRRX2; HLTF; YWHAB; ZBTB38; SMAD7; KLF10; IRF4; ATF3; RARA; VEZF1; TCF3; CREB3L2; SUB1; ZNF593; ELK3; ELF5; BCL3; PDLIM1; EGR3; SNAI2; JUNB; BMI1; MECOM; HIC2; MYRF; MLXIP; TGFB1I1; EGR1; KLF2; FLNA; EGR2; KLF9; POU2AF1; CALR; NR1D2; NFKBIB; PIR; ID3; STAT5B; ID1