Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08751 Pf-431396 GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 579 NFIX; MEF2C; E2F2; NFKB2; ZNF544; ZNF235; THRB; HES2; LDB1; IKZF1; ZNF606; ZNF154; CEBPD; THRA; TCEA2; ALX4; SOX2; AR; ZNF211; CREG1; RFX1; HOXB8; ZNF573; DCC; PRDM9; NEUROG2; ZNF117; POU6F2; PROP1; HIF3A; TULP1; TP73; TBX5; EHMT2; TBX6; PRDM14; TEF; NEUROD4; NEUROD2; MAK; SSBP3; FOXE3; ARID5A; BCL11A; RBPJL; ZNF264; ZKSCAN4; SCAI; FOXL1; MAML3; ZNF8; SRY; TBX1; LIN28A; FOS; ESRRB; ZNF550; SOX21; SCRT1; NFATC4; ZNF549; ZNF440; FEZF2; FOXH1; SIX3; TFDP3; HDAC9; EPAS1; SOX1; ZNF221; MECP2; GBX2; ZNF208; EMX1; GBX1; PDX1; ZNF358; ZNF669; ATN1; ZNF343; ZNF224; HOXD12; LZTR1; ATF6B; NEUROD6; ZNF749; BNC1; ZIC4; ZNF771; AIRE; PRDM16; ONECUT1; FOXD3; ZNF814; ZNF345; SOX14; CARF; ZNF778; BRDT; ZNF350; DOT1L; HEYL; ASCL3; TBR1; ZNF391; NHLH2; NACA2; ATF7; ZNF132; ZNF551; HAND2; HEY1; ZNF611; ZSCAN9; ATOH1; GSC2; RORB; ZNF500; BARX1; SOX5; HIPK2; CHD2; ZBTB7C; ZNF10; TAF6L; NEUROG1; POU2F3; ZNF688; ZNF816; ZNF589; ZNF362; IRF6; HIC1; MYCN; ZNF180; ESR2; ZNF257; SPI1; TCF21; ZNF134; CDIP1; SMAD6; ZNF81; HDAC5; CRX; NR2E1; ZNF304; GCM2; FUBP1; ZNF471; ZNF529; SOX18; HMGA2; PAX7; FOXF1; ZFP2; ZNF75D; NHLH1; MYNN; IKZF3; MED25; PRDM2; CDX4; RFX3; ZNF74; HLX; VSX1; HAND1; PAX1; REL; RSF1; ZIC3; IKZF2; SUPT3H; ZNF695; KLF8; HOXB1; CERS6; OVOL2; RARG; ZFY; SP4; DLX5; ZNF407; POU5F1B; ZNF467; ZXDC; GRIP1; SOX3; FOXF2; ZNF136; LBX1; ZNF112; ZNF442; NR5A2; ZNF813; CALCOCO1; POU4F3; FOXB1; ZNF682; ZNF701; VENTX; KAT2B; TBX10; ZSCAN2; FOXP3; ZNF780B; SOX17; ZKSCAN8; L3MBTL1; MAPK8IP1; ETV2; NR2F1; PBX1; SSX7; HSF4; ZBTB48; ZNF223; ZBTB7B; NPAS1; TFAP2A; HESX1; NR5A1; TBX21; NKX6-1; EYA3; TAF1C; ZNF674; RORC; PAX3; MSX2; ETV3; ASH1L; ZNF273; TFAP2B; ARHGAP35; ZNF556; KLF15; TWIST1; POU3F4; ATF3; ZNF225; TBL1Y; THAP10; DLX6; ZNF141; POU1F1; ASCL2; ERBB4; UTF1; SUPT7L; TBX4; PRDM5; AFF3; ZNF142; ZFHX2; MYF5; ZNF80; KDM4C; ZNF331; ZNF234; TLX1; FOXD2; GTF2A1; ZNF623; TEAD3; PKNOX2; MZF1; TLX3; ZNF287; ZBTB3; ZNF423; LHX3; SRCAP; TULP2; PRDM1; CD3D; CUX2; POU3F3; HOXA3; ZNF493; RING1; ZSCAN12; AFF2; HOXC8; ZNF671; LMX1B; ZBED2; CIITA; ZNF44; NOCT; CDX2; ZNF157; TONSL; GCFC2; ZFP69B; ZNF253; PRDM12; ZNF562; VHL; HMGXB3; KAT2A; ZNF222; FHL5; NR2C2; HMBOX1; ZNF41; ZBTB44; HOXB5; MLLT1; PAX4; ZNF419; MXI1; ZFPM2; PPARA; ZNF787; NR4A2; ALX3; TBX19; THAP9; NKX3-2; NR4A3; PRRX1; ZNF43; FOXJ2; RBFOX2; ZNF329; WIZ; ZNF155; HIC2; ZNF135; VGLL1; VPS72; WHSC1L1; ZNF667; NKX2-5; ZNF484; CBX2; ZNF254; ZNF710; IRF1; ACTL6B; CBX7; CREBL2; ZNF214; MAP3K10; TTF2; HNF4G; ZNF85; ZKSCAN3; ZNF334; ZNF665; SIX5; PHF1; STAT2; SHOX2; ZNF480; HIVEP3; HOXD3; E2F5; MAF; ARRB1; ZNF557; PAXBP1; ZNF586; TSHZ2; ZNF93; CNOT3; WNT4; HMGA1; TFDP2; TAF7L; MED12; ZNF764; OVOL1; FOXA2; ESRRG; GRHL2; MYEF2; TAF4B; SPDEF; LHX6; INSR; ZIM2; ZNF91; IRX4; HOXA2; ZNF174; EN2; IFNB1; ZNF711; ZNF492; SKIL; ZNF239; EZH1; ZNF215; MEIS2; RFX2; TCF4; MEIS1; ELK4; ZNF460; MBD4; SOX13; SIX6; EMX2; ONECUT2; ARNT2; E2F4; ZNF415; ZNF124; MYCBP; TOX; ARID3B; ZNF835; SPIB; SALL2; ZNF675; CBX4; ESR1; ING4; PLAGL1; SSX3; SOHLH2; TRIB3; MYT1L; EBF2; BRWD1; GFI1; FOSB; MYCL; HMX1; SIN3B; TRPS1; MDM2; ZNF528; BCL6; LHX1; TULP3; MECOM; CALR; EP300; IRF3; CBFA2T3; TDRD3; SNAPC4; ZNF83; ZNF219; CAMTA2; NR1H2; ZNF532; AES; ZNF571; FOXJ1; DBP; KLF13; BHLHE40; EGR1; KLF1; CDX1; TGFB1; KLF11; POU4F2; TCEA1; MDM4; ZNF205; SCMH1; NFIC; NR1H4; MYRF; FOXI1; LHX2; GATA1; TDP2; PAX6; NFAT5; TXNIP; NR4A1; NANOG; JUN; ZKSCAN7; RHOA; FOXA1; HOXD10; SKI; FOXN2; SMARCB1; ZNF587; ZNF770; ZNF426; ZNF536; TCF7L2; BRD2; MNX1; ZNF195; ZNF286A; BACH2; CEBPE; YBX3; LZTS1; ZNF468; ADRB2; SMAD5; CSDE1; FOXL2; SNAI2; ZSCAN18; ZBTB43; PEG3; ETV1; FOXN3; ZNF580; ST18; ZNF232; PBXIP1; ZNF22; NEUROD1; NR1H3; TAF9B; NFATC1; ISL1; PMS1; ZNF160; BNC2; EYA1; SAP18; GTF3A; ZNF432; YBX1; HDGF; NFE2L3; ZNF430; STAT4; WT1; HEY2; INSM1; ZFP36L2; OSR2; TFEC; ZIC1; HLF; EHF; ZFHX4; CREM; OLIG2; FOXG1; AEBP1; ZSCAN31; IRF8; HOXB13; IRF9; KLF9; SOX11; HMGB3; NKX2-2; ID3; AHR; EGR3; FLI1; PITX1; MEOX2; CRYM; EGR2; HMGN3; GATA6; WWTR1; ZBTB16; CBX6; GATA2; MSX1; TSC22D1; TRIM22; ZNF652; MAFB; LITAF; ID1; BHLHE41; DACH1; TBX2
Down-regulation 193 FHL2; CCNA2; ECD; PUF60; XBP1; SUV39H1; USP22; HNRNPD; PAX8; UBE2I; TP53; FOSL1; NCOA6; ATF1; ERBB2; ZNF146; SNW1; NRIP1; GTF2A2; SCAND1; HOXA5; HDAC2; RBM14; BAZ1A; MED1; MYBL2; NPAT; CCDC59; YWHAB; SFPQ; MBD2; HOXA10; CDK7; NFIL3; ARID4B; REST; SMARCE1; VEZF1; TBPL1; AFF1; CNOT1; SMARCA5; CRY1; CENPF; HOXC6; HIF1A; RNF4; HOXB7; NUP62; TSC22D2; BLM; CBX3; PHF20; BRD3; ADNP; CNOT6; SMAD4; EZH2; TBP; FOXO3; HMGB2; NRBF2; CTR9; EED; SMARCC1; COPS5; CCNC; RNF111; DEK; KDM2A; RAN; ZBTB11; TRIM32; CTCF; BAZ1B; GATAD2A; PATZ1; KAT8; HMGB1; HSF2; BRPF1; DPF2; CEBPZ; CBFB; ILF2; ASXL1; MED6; BCLAF1; TBL1X; PREB; TRIM16; RFC1; HSBP1; RAD21; ZNF281; ELF5; NR2F6; RARA; RUNX1; ATF6; WHSC1; YAF2; XRCC6; KMT2A; ZNF672; DNAJC2; ING2; ELF1; NPM1; AATF; PSMC3; SOX4; RCOR1; BRD7; TLE1; UBE2B; ORC2; HIVEP2; SF1; PCGF2; MED13; SSRP1; NFKB1; TSG101; PQBP1; STAT6; MAX; NCOA4; KAT7; MLXIP; APEX1; FOXK2; TAF9; TRIM27; MTDH; ELK3; TRIM29; CTBP1; SP3; SMARCA2; ZNF410; NELFB; BATF3; CRK; CEBPG; UBP1; TAF10; GTF2IRD1; HOXA11; UBE3A; BRD8; BMI1; LPIN2; IKBKAP; ATF4; ZBTB18; BASP1; MAGED1; PHIP; SP100; TLE4; ZNF217; PTTG1; RNF6; IRF7; RBBP4; HOXC10; ZNF512B; SMAD1; KLF10; RNF138; NKX3-1; SMAD2; NR2F2; SP110; TCF12; TBL1XR1; SIAH2; MYBL1; PAWR; RBPMS; REPIN1; EDF1; SERTAD2; ELF3; ASCL1; CEBPB; PTRF; THAP11; ABL1; PBX3; NKX2-1; NR3C1