Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08747 Gsk-1059615 GSE70138 HA1E Human 24h 1.11uM EID0001
Types Number Response transcription factors
Up-regulation 115 TCEA2; HMGB3; INSR; PHIP; ARID4B; CBX7; JUP; MNDA; HOXA10; PBX1; E2F8; PCGF2; PHF2; SOX4; CALCOCO1; BRD3; MEF2C; HBP1; TGIF1; ZNF443; SSBP3; FOXA1; IRF8; HOXC6; HDAC4; IRF9; IFI16; ZKSCAN1; BAZ2B; MED23; ZNF117; PIAS4; ZNF350; ZNF83; ZNF112; TCF7L2; TRIB3; CTBP2; GATA2; AR; CERS6; NANOG; HOXB7; BCL11A; L3MBTL1; PBXIP1; FLI1; ZFPM2; CD3D; TFEC; THAP10; AFF1; FOXN3; NAB2; TFCP2; ZNF430; HOXA11; JAK2; KLF11; TLE4; APEX1; CUX1; OSR2; IKBKAP; MYCL; SMARCC2; ESR1; SIM2; HOXA5; MYRF; PAWR; HHEX; ARNT2; CRYM; CEBPA; BNC2; ERBB4; FOSB; ZBED1; TAL1; HOXB6; HLX; TRIM22; HIC2; CITED2; HTATIP2; ARID1A; HMGB2; MAFB; CREBL2; SALL2; CUX2; MYB; LIN28A; TXNIP; SALL1; ZNF331; ZNF160; GATA6; TCF7; EMX2; ZNF91; TBX3; KLF10; RXRA; TOX3; AEBP1; SPDEF; HES1; FOXO4; KDM5D; POU2AF1; HMG20B; MEIS2; PEG3
Down-regulation 42 PAX8; FOSL1; NFKBIA; RELB; NFKB1; NFIL3; BHLHE40; TRIM29; ELF5; CBFB; PIAS2; WWC1; CCNE1; MBD2; ENO1; NFYA; RELA; GTF3A; CHD7; ATF3; CITED1; SOX10; CRY1; MEIS1; STAT3; YBX1; C1QBP; MTDH; YWHAB; NR2F1; SERTAD2; RUNX1; MNAT1; DNMT3B; ELK3; MECOM; PITX1; LITAF; FOXC1; KLF9; STAT5B; ID1