Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08745 Gsk-1059615 GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 244 TCEA2; ZNF282; PPARD; SETDB1; ZSCAN9; RING1; EZH1; RBFOX2; CERS6; MZF1; ZNF589; DDIT3; PAXBP1; ZNF133; LZTR1; ZNF787; TCF25; ZNF274; CBFA2T2; TAF6L; ZNF74; ZNF76; HDAC5; PCGF3; LDB1; E4F1; ZNF219; PRDM2; ING4; ATOH1; ZNF337; ZNF43; ZNF500; ZNF117; TBX19; ZNF211; ZNF771; NR1H2; HDAC6; ARHGAP35; CXXC1; KLF15; BCL11A; ZNF692; MBD3; SOX4; ZNF573; ZKSCAN4; ZFHX2; SSBP3; ZNF224; NR1I3; EZH2; VPS72; GTF2F1; IRF3; THRB; FOXA2; HDAC11; ATN1; NR2E1; EHMT2; SIX3; KAT2A; BARX1; BNC1; ZNF45; TRIB3; ZNF354A; ZFHX3; TAF1C; LHX3; MED24; ZNF345; KLF11; MTA1; ALX3; ZSCAN32; ZNF235; BTF3; HOXB1; SOX13; AR; ZNF91; MNX1; GBX1; PRDM10; ZBTB17; ZNF83; ZNF202; ZNF324; TBX21; NPAS1; PRDM14; CALCOCO1; ZNF212; ZNF264; L3MBTL1; HMGA2; MED15; VENTX; E2F2; SRCAP; GATA1; FOS; NEUROD6; CAPN15; MBD4; TEAD3; MEF2C; CRTC1; SOX18; GON4L; GATA2; ATF4; ZBTB48; ERCC3; HLX; MED12; HOXD13; SNAPC4; SOX11; ZNF688; HOXD1; POU3F2; CAMTA2; THRA; ZNF232; ZNF112; ZNF667; ZNF180; ZNF3; TLE2; KLF1; CBX4; CBX7; LYL1; CEBPA; ARID3B; CNOT2; TAL1; FOXA1; PBXIP1; KLF13; PCGF2; USP21; ZNF135; EGR1; SIX6; SPDEF; PCGF1; NFX1; ZNF24; SMARCB1; ZNF623; FEZF2; ZNF33B; ARNT2; ZNF141; TDP2; TFAP2A; MYRF; ZNF415; PRDM1; RUNX3; POLR3C; PIAS4; HBP1; SIN3B; YBX3; NHLH2; TRIM28; ZNF205; MYCL; ZNF467; FOXN3; FOXF2; INSR; HOXD3; PBX1; JUP; NAB2; PPP1R13L; TULP3; TCF7L2; ZNF195; IKBKAP; NONO; KLF4; MEIS2; ZIC3; KLF7; DBP; NFIC; MEOX2; ZNF432; ZNF268; ZNF665; NKX2-2; RXRA; SALL2; ARID1A; STAT4; TCEA1; APEX1; BRD4; HOXB13; ZNF131; CERS4; FOXG1; HDAC9; HMBOX1; HOXB2; PAX6; TWIST1; ZNF423; CSDE1; PLAGL1; IRF6; ZBTB20; SATB2; IRF8; CUX2; CBFA2T3; MNDA; NR0B1; SOX17; CREM; ZNF331; ST18; INSM1; KDM5D; PDLIM1; EMX2; CEBPB; ZIC1; SMAD1; HES1; HMG20B; GATA6; PEG3; FOXO4; ABL1; POU2AF1
Down-regulation 98 PAX8; TBPL1; NFKBIA; FHL2; CCNA2; MYCBP; TFDP1; SFPQ; NRIP1; ATF1; SMAD3; HNRNPD; HIF1A; MYBL2; XBP1; HSBP1; GABPB1; USP22; ZMYM2; BRCA1; ELF5; CCNC; GTF2A2; HMGN3; SAP30; VEZF1; ZBTB18; ENO1; ENY2; CRY1; TSC22D2; STAT1; MYBL1; MAGED1; NCOA4; HSF2; PIAS2; NFIL3; ELF1; ATF5; MBD2; ASCL1; AGO2; SOX10; LEF1; BBX; TMF1; WWC1; MEOX1; MTDH; BIRC2; ZEB2; TFAM; RNF6; AFF1; TRIM29; FOSL2; NPAT; PPARGC1A; THAP11; STAT3; HLTF; CHD7; MITF; BMI1; TBL1XR1; BAZ1A; ZBTB38; E2F3; NR2F2; SMARCA2; ETS1; RBBP7; RBBP4; RFX5; MNAT1; NKX3-1; HIPK3; PIR; HOXC6; NFIB; IRX5; DNAJC1; HMGB2; FLNA; WWTR1; TOB1; PTRF; YWHAB; EGR3; AHR; LMCD1; MYB; TOX3; TXNIP; STAT5B; NFATC3; NR3C1