Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08738 Vemurafenib GSE70138 HA1E Human 24h 0.04uM EID0001
Types Number Response transcription factors
Up-regulation 59 PPARGC1A; ZMYND11; MEOX1; MYCN; BTG1; TAF9B; SIM2; RNF14; ZEB2; ZNF426; SMAD3; MITF; KLF9; PURA; NCOA1; NKX2-2; TOX3; BCOR; YAF2; DEK; GATA2; JARID2; RBBP7; CRY1; HLTF; URI1; HSBP1; RAN; TRPS1; HEY2; TXNIP; ETS2; ID4; FLNA; PAX6; TBX3; PBX1; PAWR; ZBTB38; DACH1; PLAGL1; MEIS1; TRIM29; TFEC; HIPK3; ZKSCAN1; SAP30; MYB; ID1; NPAS2; ZIC1; SOX9; KLF6; AHR; CITED2; INSM1; GATA6; FOXF1; NFATC3
Down-regulation 31 TGIF2; RFX5; AIP; STAT6; PIAS1; CREB3; PCGF1; RNF111; SP3; BAZ1A; TULP3; APEX1; POU2AF1; VDR; CERS4; SOX17; NFIC; ZHX2; TRIB3; ZNF217; TCF12; BNC2; HOXD1; ARNT2; PAX5; TBL1X; MEIS2; ZFP36L1; SOX11; ERBB4; NR3C1