Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08736 Vemurafenib GSE70138 HA1E Human 24h 0.37uM EID0001
Types Number Response transcription factors
Up-regulation 73 RELB; NFATC4; SSBP2; ZBED4; DR1; ID4; SMAD6; TRAK1; NR3C1; PATZ1; MNAT1; RNF14; PBX1; HMG20A; NRBF2; SMAD2; GATA2; KLF7; TAF9; SFPQ; SMAD3; NAB1; NR1I2; E2F5; TRIP6; MEIS1; BCL3; JARID2; HOXC10; ZNF22; NR0B1; NKX2-2; MEF2A; MSX1; SPIB; ZNF304; CALR; HSBP1; NFKB1; ZNF532; DAXX; ZBTB38; ID1; ZNF467; HIPK3; SOHLH2; NCOA1; PAWR; ID3; TCF4; HDGF; PURA; NR2F1; SOX11; PBX3; HLTF; DACH1; ZHX2; HEY2; SREBF1; HOXB2; IFI16; SMARCA1; EGR3; GATA6; ZEB2; ZSCAN18; BMI1; ESR1; RUNX3; ELK3; PLAGL1; TRPS1
Down-regulation 40 SUZ12; FOSB; UBE2I; TOB1; MXD1; ST18; LYL1; GATA1; MED24; ZNF44; CREB3L1; ZNF264; KDM5D; HOXD1; MYRF; SOX10; BNC2; ATF4; ETV5; RBPJ; MLXIP; THAP11; JUP; CHD8; FOXC1; TWIST1; BTG1; NFE2L3; LITAF; INSM1; ZNF423; ZNF331; TXNIP; FOXG1; ZBTB18; ARNT2; NR4A2; TSC22D1; SATB1; NFATC3