Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08734 Vemurafenib GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 46 HES1; MNAT1; PAXBP1; PPARG; CEBPA; PREB; HMGB3; TCF7L2; ZNF32; ELF5; KDM5A; UBE2B; PATZ1; DDIT3; KLF9; TEAD4; NR1H3; ATF4; ZBTB38; BCL6; HSBP1; EN1; FLI1; HEY1; KLF11; KLF5; TRIM16; ID1; NFIB; PIR; NR2F1; ZIC1; MECOM; EGR2; TOX3; IRX5; EHF; CEBPB; EMX2; ELF3; ST18; DACH1; ZMYND8; ZHX2; TXNIP; NR2F2
Down-regulation 43 FOSB; LEF1; TCF4; RFX5; ABL1; LOXL2; AFF1; AR; CARHSP1; PCGF3; JUND; MEIS1; IRF4; SHOX2; JUNB; HAND1; KLF7; BCL11A; ZNF12; ISL1; HMGA1; RORA; TCF21; PAX5; ESR1; BNC2; NFE2; SSX1; NR0B1; FOXF2; FOXF1; LIN28A; ZBED2; PBX3; MXI1; SMARCA1; SOX9; POU2AF1; MYB; AEBP1; KDM5D; TSC22D1; SATB1