Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08694	Mitoxantrone	GSE70138	HA1E	Human	24h	0.37uM	EID0012

Response Information :

Types	Number	Response transcription factors
Up-regulation	104	TRIM22; SOX4; ZNF79; NCOA3; ZKSCAN1; TCEA2; TOX4; HLX; TSC22D3; ZNF212; PCGF3; ZNF140; HINFP; SUPT7L; TOB1; TGFB1; TP63; CDIP1; IRF5; ZIC1; KLF5; ETV5; MLXIPL; KAT7; IRF8; BHLHE40; LHX2; STAT3; MBD1; ZNF45; IRF9; CBX6; RUNX3; RXRA; ZBTB43; CALCOCO1; PEG3; NHLH2; BRD8; PDLIM1; BRD2; ZNF529; SETDB1; MYT1L; DDIT3; BAZ2A; IRX4; KLF10; ZNF211; SCAND1; IFI16; TSG101; TFAP2A; MDM2; AHR; FOSL1; NFYC; SUPT4H1; ATF3; MSC; ZNF415; BATF; GFI1; ZNF91; TDP2; RBL2; BCL3; SNAI2; SMAD5; CEBPB; STAT1; PBX3; ZNF43; ARNT2; HDAC9; CUX2; NFIB; NFE2L1; VGLL4; SP110; SOX13; KLF4; CITED2; TXNIP; SOX9; HOXB2; HLF; ZNF544; IRF7; EGR2; BTG1; SMAD1; YBX3; ZNF331; TFEC; FOSB; TRIM29; BAZ1A; MAF; KDM5D; ETS2; INSM1; NFATC3; ID1
Down-regulation	103	CCNA2; PARP1; MYBL2; PCBD1; ATF6; SMARCC1; THAP11; PAX8; SMARCA4; RHOA; GLI2; CENPF; FOXM1; BRD7; ADNP2; NRIP1; TBL1XR1; PRMT2; MYBL1; SMARCA1; IKBKAP; NR2F1; ERBB2; NR2F2; PIAS2; TRIM28; C1QBP; CALR; BLM; UBE2I; ZZZ3; CSDE1; NR4A1; PREB; AEBP1; URI1; HMGB2; CLOCK; NFE2L3; GATA6; HOXC6; NR2F6; WWP1; MYC; HMGB1; ZEB1; CREB3L2; PITX1; HNRNPD; GTF3A; ZNF587; MEOX2; NR3C2; KLF2; MEIS2; ARNTL2; ZFHX3; TULP4; HMGA1; PTTG1; TCF12; TCF4; NPM1; BCLAF1; CBFB; ZHX2; RBPMS; PAX5; HIVEP1; KMT2A; BNC2; UBP1; PITX2; HDGF; RERE; SETD2; ZBTB38; CHD7; BACH2; SOX17; TBL1X; E2F5; DEK; MLXIP; HHEX; CREB3L1; SALL1; TGFB1I1; ISL1; LMCD1; POU2AF1; LEF1; ASCL1; TLE4; ESR1; FOXF1; CEBPZ; MECOM; MEIS1; ZEB2; ABL1; PPARG; SATB1