Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08651 Gsk-2126458 GSE70138 HA1E Human 24h 1.11uM EID0012
Types Number Response transcription factors
Up-regulation 118 GATA3; SOX4; HOXA5; ING4; HMGA2; FOXO4; TCEA2; HBP1; ZNF219; E2F2; CXXC1; HMX1; EZH1; FOXM1; FOXN3; ZNF33B; ETV4; CHD2; ATOH1; NR5A1; CALCOCO1; SETDB1; DCC; PRMT2; KLF4; CDK7; POU5F1B; HMGA1; NR1I2; LIN28A; HOXC11; ZIC3; DLX4; BRD7; TRIM22; ARNT2; YBX2; RORC; LHX6; HDAC5; PFDN5; TCF7; NR1H4; NKX2-2; UBE2I; SMARCC2; INSM1; OVOL1; CDX1; CREBL2; GATA1; TDRD3; ZNF160; BANP; NPAS2; KLF2; TERF1; TDP2; HOXD1; ZNF721; DDX17; HNF4G; ZNF665; IRX4; NANOG; ZNF24; TCEA1; CARHSP1; KMT2A; TGIF1; NFATC1; PBX3; SP110; ZNF611; IRF5; TSC22D3; AEBP1; NR0B1; MED13; CAPN15; ZNF93; KLF11; NEUROD1; RAD21; FOXF2; HTATIP2; ZFP36L2; PHOX2B; IRF8; SOX11; HOXC6; MAFF; TLE2; STAT6; IRF6; KLF6; TAL1; HMBOX1; IFI16; PAX6; TCEB2; TBX3; KDM5D; CEBPB; BTG1; MXI1; PBX1; ZBTB20; BCL11B; MAFB; DACH1; ZNF91; ZNF83; FOXG1; RBPMS; TRPS1; SOX9; NFATC3
Down-regulation 63 LOXL2; XBP1; PAX8; RUVBL1; MYCBP; DR1; BHLHE40; TFDP1; MAGED1; PIAS2; CALR; NFIL3; SFPQ; WDR77; SUB1; TRIM16; TRIM32; RUVBL2; RLF; POLR3F; WT1; FOSL2; ATF5; BCL3; YAP1; NFKBIA; ERF; ZBTB18; ZMYM2; ZNF200; ZNF512B; SIAH2; MEF2A; MAX; HNRNPD; SAP30; RNF6; PLAGL2; ZNF266; IRF4; WWC1; SIX1; ENO1; LITAF; HOXB6; EYA2; SMAD1; PTRF; KLF10; AFF1; ING2; ZBED2; POU2AF1; EHF; VDR; BMI1; MEIS2; GTF2A2; LEF1; FOXC1; ATF3; PPARG; ADRB2