Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08650 Gsk-2126458 GSE70138 HA1E Human 24h 3.33uM EID0012
Types Number Response transcription factors
Up-regulation 109 SOX4; HMGA1; FOXO4; HOXA5; HMGA2; PPARD; ETV1; ETV4; TCEA2; ZNF219; HSF4; TERF1; ARNT2; ING4; HBP1; PSPC1; SMARCB1; ZNF76; COPS5; NONO; HMX1; POU5F1B; TDRD3; ZNF224; CALCOCO1; CBFA2T2; ZNF74; HDAC7; PRMT2; EZH1; TULP3; NCOA2; HOXC4; APEX1; ZNF232; NPAS2; MED15; ZNF646; SETDB1; ZNF227; ZNF358; CREBL2; ZNF45; TCEA1; NANOG; ZNF32; HOXB7; TDP2; SMARCC2; MNAT1; MYBL1; FOXM1; PBX1; FOXG1; ATF4; EHMT2; TCF7; TCF25; ARID5A; TCF15; SALL2; DDIT3; TGIF1; BAZ2B; BPTF; CBX7; ST18; ID2; HDAC9; TGFB1; OVOL2; PCGF2; ELF3; BRD8; ETV5; DEK; ZNF131; ZNF611; PRRX1; TSC22D1; SOX11; ZNF721; FLI1; SOX13; IFI16; ZNF160; NR2F1; TRIP6; ZNF117; TAL1; CTBP2; SOX17; ZNF83; MECOM; HOXB2; TRIM22; JUP; KLF4; SOX9; INSR; KLF11; HOXB6; MAFB; ZFP36L1; HTATIP2; CEBPB; INSM1; KDM5D; ABL1
Down-regulation 62 MYCBP; XBP1; ATF6; PAX8; CCNA2; BHLHE40; NRIP1; NFKBIA; SUB1; MAGED1; PIAS2; GATAD2A; NFKB1; CREB3L2; SFPQ; RRN3; TFAM; SIAH2; WDR77; IRF4; PREB; CALR; HIPK3; TMF1; SERTAD2; HSF2; ZNF516; YWHAB; RBBP7; HLTF; TEAD1; ENO1; GATA4; WWC1; LMCD1; TSC22D2; CUX1; ZNF410; KLF10; FOSL2; PEG3; SOX10; DLX2; TXNIP; ZBTB18; ZNF652; ZBED2; NKX2-1; PTRF; ZNF331; BMI1; IRX5; GATA6; RUNX1; ELF5; WT1; EGR3; HEY1; TRIM29; SATB1; ADRB2; PPARG