Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08636 Azd-7762 GSE70138 HA1E Human 24h 0.37uM EID0012
Types Number Response transcription factors
Up-regulation 54 RELB; KAT6B; E2F2; FOXO4; TRIM22; IRF9; EGR1; IRF7; CUX2; HOXB5; TOB1; ATF4; RUNX3; MZF1; SCAND1; NFKBIA; ATF3; TCEA2; CERS4; FOXA2; HOXB6; TSC22D3; MDM2; JUNB; BCL3; DDIT3; CEBPB; BRD8; SP100; STAT1; FOS; NR4A1; FOSB; SP110; ARNT2; SPIB; LMCD1; NKX2-1; LPIN2; TCF21; FOXA1; ELF3; SOX11; OSR2; FOXO1; EYA1; PAX5; MYBL1; HOXB7; PIR; MSX1; NR4A2; EGR3; TWIST1
Down-regulation 49 GLI2; PAX8; HOXA5; MTA1; ZBTB38; ARID4B; NANOG; LIN28A; ZBED2; TCF3; SKI; WWTR1; ZMIZ1; ZNF148; AFF1; CLOCK; PTRF; CREB3L2; ZNF512B; GATAD2A; UBTF; CREBL2; BHLHE41; FOXC1; FLNA; BBX; ELK3; TLE1; ZHX2; CHD1; SMAD7; ENO1; TRIM29; ZEB1; RFX5; CHD7; INSR; TFEC; MAF; TCF4; SATB2; TBX3; YBX3; EMX2; MNAT1; PEG3; MEIS1; PPARG; ADRB2