Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08634 Azd-7762 GSE70138 HA1E Human 24h 3.33uM EID0012
Types Number Response transcription factors
Up-regulation 112 FOXO4; SPDEF; MYBL2; MEF2C; RELB; HSF4; SALL2; IKZF1; ZNF589; ATF3; HDAC6; SOX3; SPI1; ARNT2; POU5F1B; NFKBIA; MNDA; ZKSCAN8; TCEA2; ZNF215; LIN28A; TSC22D3; NFATC4; OSR2; NHLH2; NANOG; CRYM; CUX2; NHLH1; CBX7; JUP; HDAC9; ZIC3; ZNF44; TAF4B; IRF8; ERBB4; INSR; NKX3-2; MZF1; MLXIPL; RBBP7; ZNF224; EMX2; L3MBTL1; TRIM22; HOXD11; DLX5; ARID5A; SIX3; PBX1; CALCOCO1; IRF1; TFAP2A; ZNF580; E2F8; KDM5D; GLI3; FOS; MEIS2; ZNF711; ST18; DLX4; HBP1; HOXD1; FOXJ1; DDIT3; ZNF423; SSBP3; THAP10; CBFA2T3; YBX3; HMGB3; CITED2; NR1H4; ZNF611; TWIST1; MDM2; NAB2; CEBPB; ESR1; ZFPM2; ZNF195; FOSB; NFE2L3; TFAP2C; NR4A1; WT1; BCL6; HMGN3; ZNF264; PIR; SALL1; ZNF160; RFX5; BRD2; MYRF; TOB1; BCL11A; WWC1; SOX17; ZNF331; TAL1; ZBTB18; RBPMS; PAX6; ZFP36L1; ZBTB20; SNAI2; MITF; CEBPD; NFKB2
Down-regulation 84 CRK; ATF6; RHOA; BHLHE40; BIRC2; CREB1; ATF1; HOXA5; HOXA10; MED27; FOSL1; NCOA1; CBFB; PPRC1; PURA; ARID4B; URI1; TRIM27; ZZZ3; BCLAF1; TBL1XR1; FOXD1; MTDH; ELK3; YAF2; HSBP1; MED6; BRD3; TULP4; ZKSCAN1; ZMYND11; SFPQ; ZMIZ1; HNRNPD; DNAJC1; BMI1; YWHAB; C1QBP; ETS1; MAGED1; YAP1; NCOA4; THAP11; NPAT; TRIM32; FOXC1; SMAD7; SMARCA2; HIPK3; RNF111; JARID2; CCNC; ZBTB38; TRIM16; ENO1; PTRF; NRIP1; MLXIP; NFIB; SMAD2; KLF2; MBD2; SOX10; WWTR1; HOXC6; NR2F2; SMAD1; FOSL2; TSC22D2; MYC; KLF6; CEBPZ; KLF9; ABL1; NR1D2; ZSCAN18; LEF1; ASCL1; TOX3; NR3C1; SSBP2; ADRB2; HES1; PPARG