Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08617 Azd-5438 GSE70138 HA1E Human 24h 1.11uM EID0012
Types Number Response transcription factors
Up-regulation 25 ZNF589; EGR1; PAX8; TCEA2; KAT2A; TFEB; SHOX2; PCGF2; NCOR2; MLXIP; MSX1; GATA2; EGR2; NR4A1; DACH1; FOSB; CEBPZ; EGR3; ZNF91; NR0B1; ZBTB38; TWIST1; HOXB7; ZNF423; TXNIP
Down-regulation 73 CREB1; ATF5; CCNA2; FOXO4; TLE4; ABT1; PNRC1; NFIL3; CITED2; JARID2; EN1; MAGED1; FOXJ2; TGIF1; BCL11A; NKX3-1; ATF4; BCLAF1; MEF2A; HIVEP1; POLR2A; SUB1; ZNF184; BTG1; ARNTL2; TBL1XR1; NRIP1; TOPORS; ZNF711; KLF3; HDGF; SUPT3H; YBX3; TP63; HMGB3; MYCL; ZFPM2; IRF1; CALR; ZBTB18; HIPK3; TCF4; YWHAB; JUP; SERTAD2; MED21; ZHX2; PTTG1; HHEX; SIAH2; TCF7L2; PHIP; PEG3; HMGN3; FOXF2; NR1D2; HMGB2; SAP30; ZNF329; ZFP36L2; MYB; ID4; ELF5; MYC; TRPS1; TBL1X; TRIM29; NFE2; NR4A2; LEF1; ADRB2; SATB1; PPARG