Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08616 Azd-5438 GSE70138 HA1E Human 24h 3.33uM EID0012
Types Number Response transcription factors
Up-regulation 246 ZNF274; PPARD; GMEB2; ADNP2; ZNF473; PPRC1; ZNF211; IKZF5; SPDEF; ZNF14; ZNF304; ZNF79; ESR1; ZKSCAN4; ZZZ3; FOXJ3; ZNF7; ZNF239; ZNF136; ZNF232; ZNF266; ZNF180; ZNF432; ZKSCAN5; ZNF23; RRN3; RLF; ZBED4; ZNF34; ZNF468; MAFB; TGS1; ZNF629; CAMTA1; ZNF268; TRIM33; ZNF45; ZBTB39; L3MBTL1; ZNF227; GABPA; GON4L; ZNF419; ZBTB48; ZNF3; KAT2A; ZNF787; ZNF222; ZNF394; ZNF576; ZNF8; ZNF200; MYNN; ZSCAN32; ERCC2; ZNF415; ZNF35; ZNF557; ZSCAN9; ZNF783; ZNF324; ZXDC; ZNF83; DNAJC2; ZNF264; CEBPG; ZNF408; OVOL2; CDC5L; ZNF273; ZNF593; RNF4; RARA; ZNF813; NANOG; ZNF195; MNT; ZNF668; TTF1; PAXBP1; ZNF134; SNIP1; ZNF562; SALL2; ZNF10; MEF2C; SIN3B; CIR1; ZNF711; NFIC; BRPF1; PPP1R13L; SP110; ERCC3; ZBTB43; ZNF263; HMGXB4; ZNF614; CERS6; BRD2; ZNF544; ZNF606; PSMC3IP; AFF4; ZNF426; ZNF350; ZNF24; HDAC9; EHMT2; SUPT7L; DDIT3; ZNF512B; SERTAD2; BRF2; NPAS2; SP140L; ETV5; ZNF443; TRIB3; HOXD3; ZNF84; NOC2L; MNDA; ARNT2; HLF; HIPK1; ZNF140; MED17; MECP2; HEY2; COPS2; RNF138; BANP; ZNF131; HCFC2; ZNF117; ZNF175; MAFG; ZNF764; ZBTB11; ZNF587; PCGF2; KLF11; THAP10; JUND; HDAC4; ZNF253; CEBPB; PIAS2; MGA; TAF1A; ZNF667; GTF2F1; RUVBL2; RCOR3; PHF20; ZFP36L2; TWIST1; IRF8; RBM39; SAP18; ZBTB7A; ZNF93; CBX6; OLIG2; PEG3; E2F3; CCNE1; ZNF331; THAP1; TAF9; HOXD1; ZNF551; BCL3; PLAGL2; PRDM2; GATAD2A; FOSL1; BCL10; NAB2; SLC2A4RG; BHLHE41; SPEN; TFEC; ZNF354A; CUX2; ZNF665; BCL6; NR2C1; MAFF; HHEX; SHOX2; HIRA; INSR; DACH1; CEBPZ; BRD4; ZNF573; MYCL; AR; ZNF43; ZNF107; KAT2B; SATB2; RXRA; CEBPD; FOS; ZNF91; KLF13; ZNF165; RERE; AHR; CHD7; AEBP1; DLX5; MECOM; DAXX; ISL1; BCL11A; MSX1; PAX6; ZSCAN18; ZMYND8; ID1; ZNF329; TXNIP; ATF3; KLF4; TOX; NUP62; ZBTB18; TOB1; ZNF423; WT1; ELF3; EYA2; MYB; FOXG1; TRPS1; NR4A2; ETS2; PBX3; EMX2; E2F2; KDM5D; TBX2
Down-regulation 131 PAX8; FHL2; BRCA1; CCNA2; ATF1; PSIP1; SOX4; ECD; NFIL3; TBL1XR1; JUN; ENO1; HOXC6; RAN; HDAC6; WWTR1; IKBKAP; ZNF292; CNOT1; NPM1; ARID5B; CENPF; SMARCC1; TCF12; PNRC1; ELF5; DDX17; DDX5; HMGB3; CUX1; ZBTB38; YWHAB; JUP; SMAD3; MKL1; CBX3; BTG1; ERBB2; HMGB1; VEZF1; APEX1; CREB3; CREB3L2; FOXM1; PTTG1; MAGED1; NCOA1; BCLAF1; RAD21; ATF5; LIMD1; RBBP4; TGIF1; BRD3; STAT6; NCOR2; CCNC; HOXC4; PSMC3; ID2; NFKB1; HMGB2; CDK8; PURA; SMARCA1; PQBP1; LMCD1; AES; PITX2; TLE4; HNRNPD; UBE2I; TRIM29; SOX10; ARNTL2; RBBP7; CARHSP1; IRF4; ZBED1; AIP; JUNB; EDF1; GTF2A2; MED13; SMAD7; FOXD1; CREB3L1; MYBL1; TCF7L1; RBPMS; HIVEP2; MBD2; NR4A1; LITAF; TCF4; TRIM16; ZNF652; PAX5; GATA6; TRIM22; MEIS2; HTATIP2; STAT4; NFE2L1; TP53; POU4F1; FOXC1; POU2AF1; NKX3-1; STAT1; CITED2; EGR2; SAP30; ID4; FOSB; NFAT5; HOXB6; MNAT1; TP63; TBX3; LEF1; HOXB7; ZBTB20; NFE2; SNAI2; KLF6; YBX3; TOX3; HES1; ADRB2; PPARG