Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08594 Canertinib GSE70138 HA1E Human 24h 0.37uM EID0012
Types Number Response transcription factors
Up-regulation 45 NR3C1; TBX2; IRF8; BATF; EGR2; AHR; TOX3; NR1H3; CITED2; TRIP6; NFE2L3; IRF9; FOXN3; HTATIP2; PAWR; TLE2; PBX1; CARHSP1; KLF4; KLF10; HES1; SATB2; ETS2; SNAI2; KLF6; OSR2; IRF7; NR4A1; ID3; BMI1; NPAS2; TRIM22; LMCD1; TGIF1; ZBTB38; ID1; EGR3; ATF3; ZBTB20; TCF21; PIR; PPARG; ESR1; MITF; BHLHE41
Down-regulation 62 NACA; SOX11; NONO; COPS5; YBX1; ZNF623; MYT1L; EGR1; MYT1; ZNF189; NPM1; NRIP1; ZNF529; SCMH1; EYA2; CDK9; BRD3; SSBP3; SOX17; ERBB4; TGIF2; AGO2; NCOA4; BACH2; HOXD3; ZNF512B; MEIS2; DDX17; EYA1; ZNF667; TLE4; ZNF93; SMAD1; BRD8; PLAG1; GTF3A; CCNE1; DLX5; ZNF107; MSX1; CHD7; ZFHX4; CREB5; HOXD1; TCEB2; ZNF43; PHOX2B; ISL1; NFIB; TOX; FOXG1; RNF111; BRD2; TRPS1; JUND; ZIC1; REPIN1; LEF1; CEBPZ; HOXC10; ADRB2; SATB1