Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08585	Afatinib	GSE70138	HA1E	Human	24h	10uM	EID0012

Response Information :

Types	Number	Response transcription factors
Up-regulation	144	TSC22D3; TRIB3; PAX8; DDIT3; NCOA3; PPARD; PCGF1; ZNF222; FOXO4; ZNF44; ATF5; ATF4; MEF2C; ST18; ZNF23; TAF12; HOXD1; JAK2; ZNF141; ZNF124; CAMTA2; HDAC9; ZKSCAN4; THAP7; CIR1; PSPC1; ZNF136; EMX2; TWIST1; CBX6; TRIM33; ZMYM2; RNF6; RBBP5; ETV5; EGR1; GTF3A; HIC2; SETDB1; ZSCAN9; ZNF45; ARNT2; CDC5L; MNDA; ZNF557; SP2; MED15; ZNF195; CREM; ZNF562; ZNF273; ZNF623; PQBP1; TDP2; MXI1; ZBTB7A; TGIF1; AATF; ZNF331; CBX7; ZNF354A; SOX5; HOXC4; HCFC2; ZNF24; ZNF430; ZNF43; ARID4A; FOSL1; ZNF117; ZNF10; KAT2B; CEBPB; HLX; TOB1; HTATIP2; ZNF184; ZNF529; NR1H4; PCGF2; ZNF768; TCF7; NFAT5; ZNF266; NEUROD1; CREG1; ZNF224; SP110; SALL2; UBE2B; MED13; NR2C1; CEBPG; TERF2; ZNF665; HIRA; THAP11; ZNF91; KLF11; MED1; ZNF93; ZNF593; NR4A1; ZNF217; ZFPM2; EP300; IRF8; AFF1; PRRX1; THAP10; DLX5; RORA; RYBP; PIR; CREB3L2; ARNTL; ZNF544; TSC22D1; MITF; ZBTB20; STAT4; ZNF264; HMBOX1; MYRF; ZFP36L2; SHOX2; ZEB2; ARID1A; ZNF267; TXNIP; CHD1; ZHX2; NR0B1; CD3D; BTG1; ATF3; VDR; NR4A2; SSX1; MAFB; WT1; BHLHE41; MAF; MSX1
Down-regulation	106	HOXA5; MYCBP; MYBL2; CCNA2; TFDP1; FHL2; BASP1; SOX4; SMAD3; LOXL2; DNMT1; PARP1; FOXO3; PSIP1; HOXA10; CDK2; STAT5B; HDAC2; EZH2; BCLAF1; SFPQ; ARID5B; GLI2; EDF1; NRIP1; MAGED1; ARNTL2; NELFB; SMARCC1; HOXA7; YWHAB; NR2F2; CENPF; HNRNPD; SMAD7; TCF12; NFKBIA; TGFB1I1; RELA; EHF; ERBB2; SIAH2; RBM14; SUB1; PIAS3; SMARCD3; VEZF1; DMTF1; KLF10; NPAT; BRD3; MYBL1; REST; UBP1; NR2F1; TGIF2; PBX1; WWTR1; MBD2; TCF7L1; KLF5; MYC; PITX1; SMAD4; HOXB5; CALR; PTTG1; ZBED1; IRX5; SOX11; TRIM16; MYB; HMGB2; KLF7; PITX2; TLE4; TCF21; HOXB6; MEIS1; TOX; ID4; TLE2; HMGB3; PAWR; FOXF1; GATA6; HDAC1; ZNF587; FLNA; RUNX1; ELF5; FOXC1; DLX2; CHD7; ETS2; ID3; PAX5; BAZ1A; RBPMS; TOX3; DACH1; ID1; TBL1X; HES1; PPARG; ADRB2