Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08559 Mk-2206 GSE70138 HA1E Human 24h 0.37uM EID0012
Types Number Response transcription factors
Up-regulation 32 TAF5; POU4F1; MYB; IRF6; MED23; LYL1; CBFA2T3; INSR; BCL11A; EMX2; MNDA; HOXC6; BRD2; YBX3; IFI16; ZNF22; IRF1; TFEC; KLF4; BACH2; HMGB2; EHF; BHLHE41; ZBED2; CD3D; ID3; MYCN; SATB1; MECOM; ERG; ESR1; POU2AF1
Down-regulation 31 LOXL2; ATF5; BHLHE40; TGFB1; AHR; ID2; MKL2; RXRA; CALR; NR2F1; FOXF2; CTNNB1; DDIT3; RUNX3; TSC22D2; NKX2-1; CITED2; ELF1; MYRF; HLF; FOSL2; RBPMS; NR1D2; ASCL1; TBX3; FOXF1; NR4A2; HES1; PPARG; ADRB2; ZNF586