Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08555 Palbociclib GSE70138 HA1E Human 24h 0.04uM EID0012
Types Number Response transcription factors
Up-regulation 33 ZNF589; TCF3; TOPORS; TGFB1; PBX2; JARID2; MED14; RNF141; NCOA1; DEAF1; ID1; ZMYND8; TGIF1; EGR2; IRF7; MXD4; CCNC; DNMT3B; CTR9; KLF10; TLE2; NKX2-1; ZNF232; ZBTB16; ZEB1; CITED2; ZBTB18; ZFP36L1; CD3D; MAFB; ESR1; NR4A2; ID3
Down-regulation 62 PUF60; MNDA; MED24; SOX15; RBM39; MEOX2; RLF; NR2E1; HSF1; IRF6; THAP11; ARNTL2; BTG1; NR1H4; FOSL1; EMX2; LITAF; ELF5; PIR; CTNNB1; NPAS2; TLE4; BNC2; POU4F1; RORA; STAT4; HOXA11; TFEC; SNAI2; FOXG1; TP63; YBX3; PLAGL1; KLF5; PAWR; ARNT2; MEIS2; NR2F2; TCF21; KLF9; AEBP1; ISL1; SOX10; HHEX; KDM5D; ZNF264; CTBP2; KLF4; OSR2; FOSL2; TRIM29; INSM1; DACH1; HEY1; FOXC1; WT1; ID4; BHLHE41; TOX3; ADRB2; GATA2; SATB1