Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08551 Palbociclib GSE70138 HA1E Human 24h 3.33uM EID0012
Types Number Response transcription factors
Up-regulation 333 RELB; ETV1; BRCA1; ZBED1; OLIG2; WHSC1L1; ZNF141; EGR2; PRDM5; POU4F2; THRB; CUX2; PAX7; ESRRG; SOX4; ZNF208; ZNF273; ZNF44; PRDM9; POU6F1; ZNF671; NCOR2; PRDM14; ZNF682; NEUROD2; HABP4; SP4; ZNF549; ZFY; NR2F1; FOXD2; NR6A1; ZNF235; ETS2; ZNF440; ZIC3; KDM4A; NFE2L3; ZNF701; NKX2-2; PAX1; NEUROD4; AEBP1; ZNF550; RBPJL; ZNF814; ZNF3; ZNF606; TCEA1; ZNF532; ZNF695; RFX3; HOXA3; ZNF358; DCC; ZNF257; ZSCAN2; FOXE3; GCM1; HOXB9; ZNF117; PROX1; TCFL5; NHLH1; HNF4G; EGR4; ID1; MAFG; TFDP2; ASCL3; TBX5; ZNF764; DLX6; ZNF225; NFIX; PPP1R13L; POU3F1; POU3F4; HESX1; ZIM2; ZBTB16; FHL5; ZNF654; ZNF507; NEUROD1; ZNF154; ZNF419; ZNF33B; ZNF10; ZFP36L2; SOX21; ZNF254; MAPK8IP1; ZNF492; ZEB1; ZNF140; NEUROG1; MED31; NR3C1; ZNF415; SMAD9; ZNF75D; HOXB6; POU5F1B; SSBP2; CHD2; NFX1; NR1I2; MYB; ZNF407; ZNF223; NR5A2; NR4A3; ZNF264; CDX2; ZBTB6; ZSCAN18; NR3C2; STAT2; ZNF200; KLF12; TSC22D1; HOXA2; ZNF623; SOX18; THAP9; ARID3A; NCOA1; MTF1; ZNF536; MED12; SOX3; ZNF587; HOXC13; ZNF510; NANOG; ZNF688; ZNF253; ING4; THAP10; VGLL1; MDFI; HMG20A; EBF2; ZNF493; SSX3; HNF1B; ZNF211; TTF2; NHLH2; IRF5; IRF7; LHX6; ZNF7; ID4; ZNF334; TAF9B; ZNF134; ZNF180; FEV; ELF3; RXRG; FOXJ2; ZNF268; HLX; ZBTB25; HOXB5; FOXA2; ID3; ZNF107; HLF; ZNF667; BRWD1; BLM; RING1; ZKSCAN7; ZNF112; UBE2B; ALX1; SNAI1; MYF6; HOXC11; PRRX2; ZNF443; LIN28A; TGS1; ZNF813; EP300; ZBED2; ADNP; PLAGL1; BACH1; ATOH1; HBP1; TCF12; MBD1; RNF10; BARX2; TFEC; ZNF552; ZNF586; ZNF573; ZNF571; CBX5; ZNF43; ZNF131; RCOR1; TAF4B; ZNF426; NLK; DNMT3B; LPIN2; BHLHE41; NKX2-1; RFX2; ZNF93; FOXO1; BCL11B; ZNF135; DACH1; ZNF835; ZNF529; PRRX1; L3MBTL1; ZNF22; PREB; SNAI2; CREM; GFI1; ERG; NFIC; CDX1; ZNF711; ATF3; CTCF; TFCP2L1; DLX5; E2F3; HOXB13; TCF7L2; ZNF195; PHOX2A; SP2; ZNF544; PRKDC; SMAD4; EHF; MAGED1; TXNIP; E2F5; CERS4; KLF5; IRF6; MLXIP; SSX1; HDAC5; SAP30; HAND1; SPIB; AFF1; NR4A1; INSM1; GTF2I; IFI16; TGFB1I1; PURA; REL; ZNF665; RUNX3; HOXB2; ZNF721; NR0B1; INSR; CBFA2T3; NFIB; TOX3; PBX1; TLE2; MLLT10; NCOA2; NR1H3; PPARGC1A; EN1; KLF6; PBX3; CEBPB; ZNF551; PHOX2B; ELK3; MXD1; HMGB1; ZNF304; CREBL2; ZNF329; ZNF160; IRX5; DAXX; SOX11; ZNF232; HOXC10; HOXD1; HEY2; SMAD2; KDM5D; STAT4; GATA2; ZBTB20; CHD7; ZNF165; HOXB7; NFATC1; MAF; HHEX; PDLIM1; BMI1; SOX10; SATB1; ZNF91; ISL1; PIR; TCF4; MYCN; HOXC6; ADRB2; MEIS1; EGR3; MITF; FOXC1; PPARG; NR4A2; ESR1; HEY1; ASCL1
Down-regulation 119 CREB1; PSIP1; NKX3-1; CCDC59; BTAF1; BBX; SMARCB1; TAF1; FLNA; ZFP36L1; ZNF146; ITGB3BP; CDC5L; EDF1; ZNF593; MEIS2; BRD2; KDM2A; TFAM; BCLAF1; JAK2; ZZZ3; PPRC1; EMX2; CARHSP1; BNC2; STAT6; MED24; WWTR1; KLF4; THAP7; UBE2L3; PEX14; TAF10; ZBTB1; MEF2C; DEK; ZNF692; NPM1; SUZ12; EHMT2; ATF7IP; FOXD1; CNOT2; ZBTB11; TGFB1; NRIP1; CEBPG; HIPK1; CDK9; TOB1; IRF8; WWC1; PCGF2; RBM39; SIRT7; ELF4; RNF6; ZFHX3; PA2G4; CCNT1; CSDE1; CBX4; TADA3; RFX5; ZHX2; CENPF; DNAJC2; UBP1; AIP; RNF138; ZBTB7A; ARNTL2; MLX; YBX3; AES; HIC2; RBBP7; PTTG1; DLX2; HLTF; ZNF652; PAX5; ING3; ZBTB38; TRIM16; SP3; CENPB; RBL2; STAT1; ATF4; IRF1; IKBKAP; TBL1X; BTG1; PAX6; CREB3L1; PAWR; BAZ1A; TBX3; TRIP6; KLF2; MED1; CHD1; SIAH2; PITX1; POU2AF1; CRYM; RBPMS; JUP; TLE4; JUND; ABL1; SOX9; KLF9; ZBTB18; MAFB; CEBPZ; EYA2