Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08465 Mitoxantrone GSE70138 HA1E Human 24h 0.12uM EID0011
Types Number Response transcription factors
Up-regulation 80 TP63; HOXD1; HDAC9; MDM2; TRIM22; SUPT7L; ZNF611; EGR2; ZNF536; CREB5; BCL10; NRBF2; THAP10; ARNT2; IRF9; DDIT3; PHF20; SNAI2; ZNF654; ZNF160; HMGXB4; PEG3; POLR3C; ZNF692; MED17; TBX3; TOB1; ZNF415; HIC2; RNF6; ISL1; CEBPB; ZNF665; YAP1; TRIB3; ETV5; MAF; ATF3; RUNX3; STAT1; ZNF264; ZNF83; ZFPM2; NR0B1; ZNF468; TRIM16; MYRF; JUP; OSR2; ZKSCAN1; SMARCA2; ZNF721; SP110; VDR; ZNF532; IRF8; HOXA1; TGIF1; IFI16; FOXF2; KLF5; PBXIP1; IRF4; TWIST1; ELF4; HIRA; TSC22D1; ETS2; LITAF; DLX5; FOXO1; TFAP2C; ST18; BHLHE41; SOX9; PBX1; TRIP6; AHR; MEIS2; ID1
Down-regulation 72 CCNA2; NRIP1; MYC; PARP1; RBM14; FOXM1; HNRNPD; CARM1; HCFC1; CENPF; HDAC6; NPM1; WHSC1; SUMO1; PIAS2; KMT5A; HMGB2; PTTG1; ATF6; MAZ; GABPA; MBD2; CTBP1; SMARCB1; RHOA; KMT2A; NR2F2; SMARCC1; SFPQ; UBE2B; CUX1; CCDC59; BRIP1; CNOT3; TAF9B; BLM; YBX1; WWP1; CHD1; RLF; FOXD1; CNBP; PITX2; ZNF32; MEF2A; FOSB; GTF2I; RBBP4; PURA; FLNA; SMARCE1; ZNF165; TGFB1I1; KLF7; HOXC10; CHD7; KLF6; ASCL1; PPARGC1A; ID4; MECOM; MAFB; ZHX2; ERG; GLI2; NFATC3; ZIC1; MEIS1; THAP11; SATB1; PPARG; TBX2