Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08464 Mitoxantrone GSE70138 HA1E Human 24h 0.37uM EID0011
Types Number Response transcription factors
Up-regulation 157 CDIP1; NR1H2; TP63; LHX3; ARNT2; ING4; TCEA2; CBX7; ZNF79; ZBTB17; SUPT7L; ZNF557; HDAC9; ZNF268; JUNB; ZXDC; HOXD1; ZNF419; ERCC3; IRF9; THAP10; CALCOCO1; ATF3; PPP1R13L; L3MBTL1; ZNF211; KLF4; IRF6; TBX19; ZNF654; CAMTA2; CEBPB; ZNF667; TFAP2A; ETV5; KLF5; NHLH2; CREBL2; ZNF665; SOX4; MDM2; ZNF140; MAF; SOX18; ZNF91; ZNF112; CEBPD; ST18; TRIM29; SOX3; SOX2; JUP; OVOL2; ZNF43; TRIM22; ZNF232; CERS4; ZNF274; ZNF10; SCAND1; RING1; DDIT3; ETV1; ZNF136; BCL6; ZNF223; TRIB3; ZNF180; ZNF606; CDK9; ZBTB43; EP300; PIAS4; PFDN5; SOX9; DLX5; CUX2; HBP1; PEG3; MEF2C; SNAI2; ZNF222; CXXC1; ZNF227; ZNF331; SP110; ZNF432; EN1; FOXF2; ZNF45; ZNF195; TDP2; SOX15; ZNF264; TFAP2C; ZNF3; FOSL1; ZNF219; SOX13; ZNF133; TWIST1; RXRA; TSC22D3; TOB1; ZNF532; MAFF; MNT; ZNF44; INSM1; ZKSCAN7; KLF11; SP140L; VDR; IRF7; ZBED2; ZNF415; ISL1; TBX3; TGFB1; KDM5D; PBXIP1; IRF8; ZNF239; BHLHE41; SALL2; HLX; ZSCAN18; IFI16; NKX2-1; ZNF512B; ID1; BCL11A; PBX3; PBX1; FOXG1; ZFP36L2; FOXA2; YBX3; BTG1; SHOX2; ZNF423; SOX11; DACH1; AR; BRD4; ERBB4; EYA1; ELF3; RUNX3; EHF; HEY1; SPDEF; EMX2; MEIS2; ESR1; THAP11; NFATC3
Down-regulation 94 CCNA2; PARP1; MYC; PCBD1; RBM14; RHOA; HNRNPD; ECD; PAX8; ATF6; TBL1XR1; SMARCC1; CENPF; VEZF1; NPM1; ZBTB1; MAGED1; HOXC6; XBP1; BCLAF1; CREB3L1; ZFP64; ZNF146; ENO1; REST; CBX5; RUVBL2; CUX1; YWHAB; SFPQ; HMGB3; JARID2; HMGB1; SSRP1; PTTG1; SMARCA5; KLF6; DNMT3B; AGO2; HMGB2; NFIL3; HLTF; REPIN1; MAZ; ELK3; CBX3; SAP30; NFKB1; NR2F2; KLF2; FOXD1; BMI1; IRF4; WWTR1; TCF12; MLXIP; SIAH2; ZBTB18; TBL1X; HOXA10; TGFB1I1; MYBL2; HDGF; MTDH; IRX5; NCOA1; ARID4B; ZEB1; HOXB7; SOX10; SMARCE1; CREB3L2; NR2F1; RREB1; AFF1; MEOX2; ZEB2; TLE4; BRCA1; CHD1; NR2F6; SATB2; RBBP4; CBFB; PURA; ZBTB38; FOXC1; ID2; HOXC10; EGR3; LEF1; PSIP1; TCFL5; TBX2