Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08424 Gsk-2126458 GSE70138 HA1E Human 24h 0.12uM EID0011
Types Number Response transcription factors
Up-regulation 106 SOX4; HDAC6; EZH1; ING4; CREBL2; TCEA2; NONO; HBP1; CEBPD; ZBED1; MXD3; ZNF358; BPTF; TCF25; ZNF688; GTF2F1; HDAC5; FOXM1; SCAND1; ZNF33B; CALCOCO1; INSR; KMT2A; CBX7; ZNF580; CBFA2T2; MZF1; ZNF611; BRD3; FOXO4; MTA1; PFDN5; TCF7; JUP; TAF10; ELF3; ETV1; NR1I2; HOXC4; ZFHX4; TGFB1I1; LPIN2; BRD8; ZNF219; SMAD6; TCEA1; HMGA1; COPS2; ZNF160; MED14; MAFB; LYL1; ETV4; TULP3; ZNF195; ZNF423; CXXC1; AEBP1; FOXG1; KLF13; FOXN3; SMAD2; AES; TCF7L2; EN1; MAFF; PHF20; TFCP2L1; APEX1; ZNF415; KLF2; NR0B1; JUND; FOXO1; ZNF83; CEBPB; ZNF91; CARHSP1; SALL2; ST18; ZNF32; ZNF430; PNRC1; ARNT2; REPIN1; ETV5; NANOG; DMTF1; POU4F1; HOXA5; ZBTB20; INSM1; ID1; YBX3; ZBTB16; KDM5D; ID4; HOXC6; KLF11; THAP11; TRIM22; HES1; PPARD; HMG20B; PSIP1; NFATC3
Down-regulation 51 NRIP1; MYCBP; XBP1; NFKBIA; RBM14; NFIL3; GTF2A2; TRIM16; UBP1; ENO1; YWHAB; LEF1; MITF; WDR77; TFAM; SIAH2; SFPQ; PREB; TSC22D2; CALR; FOSL2; PIAS3; WT1; NFKB1; GATAD2A; BMI1; RAN; NCOA1; ZEB2; CHD7; SUB1; MAGED1; SSX1; IRF4; ZBTB18; NFE2; SMAD5; RUNX1; FOXF1; AFF1; TCF21; TLE4; BAZ1A; MEIS1; NR2F1; TBX3; PIR; SNAI2; PPARG; ADRB2; TBX2