Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08421 Gsk-2126458 GSE70138 HA1E Human 24h 3.33uM EID0011
Types Number Response transcription factors
Up-regulation 191 SOX4; KDM5A; EZH1; VGLL4; TCEA2; FOXM1; CBX7; INSR; ZNF112; ING4; SETDB1; LZTR1; CEBPB; ZNF671; GTF2IRD1; ZXDC; ARNT2; BAZ2A; TLE2; CALCOCO1; HSF4; ZNF212; MED15; ZNF83; ZBED1; THAP10; ZBTB17; BAZ2B; ZNF184; TCF25; CAPN15; BTF3; NONO; TCF7L2; ZNF33B; SSBP3; CDK7; ZNF688; FOXO4; KMT2B; ZNF532; ZNF227; TCF20; NR1H4; ETV4; ZNF768; ZNF354A; SALL1; BAZ1B; CEBPD; SMARCC2; TFCP2; LHX2; ZNF195; BANP; ZNF345; SAFB; PIAS4; HOXB7; HBP1; AES; TCEB2; HDAC9; MZF1; HDAC7; ZKSCAN7; HOXD1; KLF3; BPTF; ZNF580; FOXJ3; MEIS2; HMGA2; TULP3; ZNF141; ZNF358; CNOT2; ATOH1; ZNF282; DDX17; MED14; USP21; ARID4A; L3MBTL1; ZNF117; PFDN5; PAX5; ZNF500; BRD7; CUX2; ZNF217; HMGA1; DLX5; BRD3; WNT4; FOXN3; MTA1; ZFHX3; ZNF32; ZNF180; NR2C1; ARID1A; SKI; NR2F1; CBX5; ZNF516; TDP2; RERE; ELF3; FOXA2; NPAS2; ZNF432; PHF20; HOXC4; CBFA2T2; ZNF415; HDAC4; ZNF43; PLAG1; SALL2; ZMIZ2; SOX13; ETV5; HOXB13; HOXB5; ZNF302; IRF8; LPIN2; TGIF1; ARID4B; ZNF593; APEX1; NR4A2; BACH2; SOX9; TBX21; DDIT3; YEATS4; TGFB1; EN1; TRIM24; CHD9; BCL11A; CIZ1; DMTF1; ST18; HOXA10; MED23; TCF7; NFE2L3; TSC22D1; PBX1; HIRA; ZEB1; ZNF232; TRIM22; ZHX2; ID1; ZBTB20; NR2F2; PAX6; MYCL; HOXA5; CEBPZ; ZFP36L1; PNRC1; ERBB4; DACH1; MNDA; PBXIP1; ZBTB16; AEBP1; TWIST1; TBL1X; MYRF; TBX3; HOXB2; YBX3; RUNX3; ASCL1; MSX1; HMG20B; HES1; MAFB; SOX17; THAP11; TRPS1; ID3; MECOM; POU2AF1; ABL1
Down-regulation 62 PUF60; MYCBP; NFKBIA; LOXL2; XBP1; BHLHE40; GTF2A2; MITF; NUP62; BATF3; SFPQ; NFYA; PLAGL1; TRIM16; SOX10; DR1; MED6; ENO1; PTRF; NFIL3; GABPB1; HAND1; AGO2; MLX; STAT3; MAGED1; PPRC1; NAB1; CCNC; SIAH2; PIR; NFKB1; IRF4; PDLIM1; ZNF410; CDYL; HLTF; CRY1; DNMT3B; PTTG1; LZTS1; RUNX1; ERG; HIPK3; NR4A3; ZEB2; ENY2; LMCD1; BBX; ZNF512B; ELF5; FLNA; WWTR1; ATF3; ELK3; IRX5; MYB; EGR3; SNAI2; ADRB2; PPARG; TBX2