Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08297 Saracatinib GSE70138 HA1E Human 24h 10uM EID0011
Types Number Response transcription factors
Up-regulation 52 CEBPD; PAX8; MXD3; ING4; POU4F1; ZNF354A; NAB2; CREBL2; NR1H4; ZNF580; ARNT2; ZNF205; TERF2; RBBP7; ETV1; ZNF219; NR0B1; CEBPZ; MNDA; PCGF2; SMARCC2; NFE2L3; SAP18; SREBF1; TRIB3; KDM5D; ESR1; SP110; CBFA2T3; ZNF721; TXNIP; SALL2; TCF7; INSR; IFI16; HDAC9; TFAP2C; CITED2; CEBPB; PBXIP1; AEBP1; PHOX2B; PBX1; MYB; FOXF1; RFX5; ZHX2; THAP11; TBX2; TOB1; KLF11; EHF
Down-regulation 55 BHLHE40; MYC; ENO1; ETS1; CREB3L1; CRY1; XBP1; MEF2A; EGR2; KLF10; AGO2; TSC22D2; SKI; NCOR2; ZEB2; PLAGL1; RNF111; CREB3L2; ZMIZ1; ELK3; ARID5B; MEOX1; HMGA2; TRIM24; NR1D2; ID3; PITX2; HES1; NR4A3; TOX3; MYCN; FOSL2; JUNB; HLTF; EGR3; NKX2-2; ZIC1; TAL1; FLNA; ZBTB38; SMAD7; NKX3-1; TRPS1; TGFB1; NR2F1; PEG3; ERG; TCF4; SNAI2; TRIM29; EGR1; MAFB; ID1; PPARG; ADRB2