Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08254 Geldanamycin GSE70138 HA1E Human 24h 0.12uM EID0010
Types Number Response transcription factors
Up-regulation 52 SOX2; TAF7; TFEC; CEBPB; FOXE1; HDAC4; SOHLH2; TOX3; NANOG; CEBPA; ANKRD1; NR2F1; FOSL2; ZNF587; AGO2; MYB; ATF5; ZNF512B; ZSCAN18; PHF1; ADNP2; AFF1; LIN28A; ISL1; PRKDC; LITAF; HLX; SALL1; MAGED1; KLF2; KDM5D; SIAH2; AR; ETS2; STAT6; DNMT3B; SHOX2; ASCL1; SFPQ; HEY1; MNDA; TRIM24; NKX2-1; PEG3; NCOR2; MAFB; TRIM22; BCL3; TBX3; GATA2; TOB1; CITED2
Down-regulation 45 PSIP1; KLF6; SMARCA5; NFX1; NFIB; ATF4; EGR1; ACTL6A; KDM4C; PSMC3; MED21; GTF2I; APEX1; NFYB; PAWR; KLF11; KLF10; NFATC3; RUNX3; ZFPM2; CHD9; GATA6; TCF12; ZBED2; ZFP36L2; ELF3; SOX9; FOXD1; ST18; ELK3; PAX5; STAT1; ATF3; SNAI2; YBX3; HOXA5; MEIS2; BTG1; CREB1; OSR2; DACH1; MEIS1; ETV1; SATB1; TBX2