Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08253 Geldanamycin GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 152 STAT5B; ZNF274; CEBPD; CHD2; ZNF33B; TCEA2; ZNF446; THAP10; ZNF384; ZFY; EZH2; PHF8; HOXC11; SRY; CBX7; ZNF394; HMG20B; ZKSCAN8; CASZ1; MNDA; ATF7IP; PAXBP1; KDM5A; ZNF442; ZIC3; HNF4G; JAK2; BPTF; USP16; FEZF2; SIX6; FOXJ2; PPARD; ZNF473; RHOA; HDAC5; ZSCAN18; TLX3; CREG1; RORA; CDC5L; WNT4; ZNF334; POU1F1; TBX19; ZNF45; TEAD3; TRIM28; ZNF287; MDM2; ZNF141; DLX5; HLX; RARG; STAT2; TRRAP; LHX3; BARX2; MKL2; ZBTB44; FOXA2; MZF1; SETD2; GRHL2; ZNF211; NR2E1; ZNF133; SIM1; PEG3; EMX2; ZNF219; OVOL2; CDK7; ARID4B; CNOT2; HCFC1; NLK; IRF6; PBXIP1; BATF3; SIX3; E2F8; PLAG1; SUPT5H; TRIP11; OSR2; SIAH2; SHOX2; NR1H4; EHMT2; BCL11A; ZNF528; NR1H2; SALL1; ZNF574; ZNF415; PGR; HMGB2; KDM5D; CITED2; MAGED1; KLF5; SSBP3; HOXB2; PIAS1; ZNF226; MTA1; DBP; CALCOCO1; ZNF282; FLI1; ZNF117; PAX6; HEY2; HIC2; RBPJ; ERBB4; ZSCAN31; HOXD11; RREB1; FOXG1; CBFA2T3; CEBPB; ZNF467; RNF6; HOXC10; SOX17; ARID1A; PAWR; AFF1; NFE2L3; TFCP2; RUVBL2; FOXO1; SPEN; TCF4; MED24; PBX1; TCF21; YBX3; NFE2; EYA2; IRF8; BACH2; MYRF; ZNF91; ESR1; ZBTB16; MEIS2; MEIS1; IKZF1; MEF2C
Down-regulation 94 LOXL2; TLE1; HIF1A; EGR1; FOSL1; CBX3; ZMIZ1; BRCA1; KLF7; USP22; TFDP1; FOSB; KLF6; TSC22D3; ZNF593; JUN; HSBP1; SOX4; CBFB; HNRNPD; PSMC3IP; ZBTB18; ATF3; WDR77; ELK3; ZNF562; CREB5; KLF2; MBD2; BHLHE40; ZZZ3; SIX1; MGA; SFPQ; ETS1; SP100; GATAD2A; E2F3; SERTAD2; CRY1; ZNF217; BBX; NPAS2; KLF10; SMARCC1; SCAND1; ENY2; TSC22D2; XBP1; TBPL1; DMTF1; YWHAB; ID2; PRRX1; HLTF; ZNF32; MED1; SAP30; RFX5; BIRC2; ID3; ZNF160; DLX2; ZNF281; ID1; ZFPM2; HMGA1; TSC22D1; ZNF423; CHD9; AHR; ABL1; TBL1XR1; ZNF721; ZNF512B; RUNX1; SNAI2; HTATIP2; LMCD1; GTF3A; TOX3; NRIP1; PBX3; NFIB; BASP1; CREB1; ZBTB38; TGIF1; IFI16; THAP11; KLF9; TOB1; MYBL1; TXNIP