Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08251 Geldanamycin GSE70138 HA1E Human 24h 3.33uM EID0010
Types Number Response transcription factors
Up-regulation 106 SSBP2; CEBPD; FOXO4; E2F8; CCNA2; HMGB2; ZNF33B; KDM5A; TAF5; BAZ2B; NR4A2; CDK8; NR3C1; ZNF331; NCOA1; RFC1; BRD8; IRX5; RAD21; MYNN; PHF8; ZNF45; KDM5B; CBX5; MNDA; PFDN5; PBXIP1; CALCOCO1; CENPF; FOXJ2; CITED2; PRDM2; TCFL5; ZNF304; ZNF248; CREG1; ZNF394; SUPT5H; SAP30; PBX2; ZNF384; NAB1; PIAS1; ZNF175; PSPC1; SMAD4; MED21; LPIN2; ZNF544; ZMYM2; ZHX2; PTTG1; ZNF165; ATF1; TFDP2; MEF2A; SALL2; CBFA2T3; RNF6; DNAJC1; PATZ1; ARNT2; ZNF184; ELF1; HIPK1; ERBB4; JUP; HMGN3; HIC2; CALR; TRIB3; LITAF; BCL11A; ATF7IP; TCF7L1; HDGF; EHF; ING3; DDIT3; PAX6; TCF7L2; MYB; BMI1; SMARCA2; PBX1; MAGED1; SOX10; TRIP6; RXRA; FOXO1; TBL1X; ETS2; SOX11; FOXF2; ZFPM2; PITX1; ELF5; CHD7; POU2AF1; EYA2; NR1H2; FOXF1; AEBP1; TXNIP; MEIS2; CREB1
Down-regulation 99 FOSL1; NFKBIA; MYC; JUN; TLE1; BHLHE40; EGR1; DAXX; SOX4; HES1; FOXO3; DRAP1; TWIST1; ELK3; KLF6; GABPB1; ZMIZ1; ETS1; PRRX1; LMCD1; SIX1; RFXANK; KLF7; MAFG; CARM1; HIF1A; AATF; HOXA10; EGR3; BATF3; GATAD2A; SP140; BCL10; SNAI2; DLX2; TBX3; POU5F1B; SMAD2; SLC2A4RG; NKX3-1; PREB; BIRC2; EGR2; NPAS2; MED1; NFIC; SMARCE1; YWHAB; SCAND1; APEX1; KLF10; CBFB; RUNX1; NCOR2; MAFF; HOXB6; KLF4; MEOX2; BATF; RUNX3; PTRF; JARID2; SOX9; C1QBP; NR2F6; ETV4; RBBP7; TSC22D3; SUB1; SALL1; DMTF1; IRF7; MAF; IRF4; FOXG1; HDAC9; PQBP1; PLAGL1; WT1; TSC22D2; PEG3; FLNA; NFATC3; ETV5; STAT3; MYBL1; FOXD1; RBBP8; ID2; SATB2; HOXC6; RELB; BHLHE41; MSX1; ZBTB18; MAFB; MEIS1; ADRB2; TBX2