Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08250 Geldanamycin GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 639 SSBP2; PRDM14; CEBPD; SRY; FOXO4; CHD2; HOXC11; ZNF33B; ATOH1; KDM4C; ZKSCAN8; ZKSCAN3; HR; SP4; ASH1L; HDAC5; ZNF384; SSX7; SHOX; ZNF286A; MNX1; PRDM5; ZNF391; THRA; RARG; ZNF480; NR6A1; FOXA2; PAX9; BARX2; HOXB13; TULP2; TBR1; SSX3; PPARA; ZNF282; PBXIP1; POU3F1; RORC; ZNF606; SIX3; CCNT1; ZKSCAN5; FOXH1; NEUROD6; ASCL3; SOX5; ZNF394; MDM2; ZNF415; ZNF701; POU2F3; HSF4; GBX1; ZIC3; SUPT6H; EYA3; ZBTB44; ZNF154; CIITA; ZNF556; ZNF446; RFX3; HNF1A; NR3C2; POU4F2; DBP; ZNF132; SSX1; SMARCD1; HMX1; ZNF507; NR2C2; THRB; KAT5; ARHGAP35; STAT2; MAML3; POU6F2; BARX1; NFKB2; GRIP1; TULP1; ZIM2; PCGF2; SIX6; POU6F1; APBB1; TEF; ZKSCAN4; SOX21; IKZF2; ZNF550; ZNF442; ATF7; ZNF695; FOXN1; TLX3; ZNF814; RUNX2; NHLH1; TAF1; NEUROD4; EHMT2; MYOG; ALX3; MED25; ZNF34; CRX; ZNF8; OLIG2; ZNF467; PRDM9; TFDP3; YBX2; NRF1; ARID3B; PIAS1; PRDM1; ZMIZ2; ZNF214; ZNF671; PAX7; SCRT1; LHX3; ZNF324B; RFX2; SSBP3; ZNF274; ETV3; HOXC8; OVOL1; HNF4G; WHSC1L1; SOX30; CBFA2T2; TAF1C; SPI1; HDAC11; ONECUT2; ZKSCAN7; BRDT; ZNF408; SP1; GTF2IRD1; CBX2; ZNF460; ZNF235; EZH1; EMX1; ONECUT1; FOXE3; CRTC1; HIPK2; SETD2; NLK; KLF15; TBX4; ZNF816; TP73; KDM5A; DCC; TBX5; FOXB1; ZNF223; CASZ1; ZNF239; MZF1; NKX6-1; ZFY; TBX19; ZNF75D; PKNOX2; VENTX; SETDB1; AIRE; RXRG; HOXC13; ZNF835; USF2; HIVEP3; ZNF202; CLOCK; ZNF444; PAX4; NKX3-2; AES; THRAP3; ZNF225; MDM4; ZBTB39; PROP1; IRX5; PEG3; ZXDB; NEUROD1; ZNF197; ETV7; BNC1; SOX13; FOXD3; CALCOCO1; CHD3; ZNF345; MAP3K10; ZNF749; ZNF205; POU2F1; VAX2; ZNF334; ZNF221; NPAS1; CBX7; ZFP37; ATF7IP; ZSCAN32; ZBTB3; ARRB1; SOX14; DMRT1; CREG1; DLX6; NEUROG1; TSC22D4; NFIX; ZNF141; PPARD; ZFHX2; HOXD1; USP21; ZNF771; LITAF; TFAP4; AFF3; RFX7; NFYA; PITX1; BCL11B; ZNF484; ZNF135; IKZF4; HEYL; ZNF549; NR2E1; ZNF212; FOXL1; RBPJL; ZNF510; ESR2; PAX3; EYA1; GATA3; PITX2; OVOL2; TAF7L; CIC; ZNF614; TGS1; ZBTB24; MYOD1; NRL; MYT1; STAT5B; ZNF143; SALL2; SMAD5; ZBTB7C; ZNF500; GCM1; PBX2; SOHLH2; TRIM25; ZNF81; ZNF780B; ZNF134; CDIP1; ZNF407; MTA2; MAK; ZBTB40; TRIP11; LMO1; HES2; ZNF669; LZTS1; CDX2; AR; IFNB1; GRHL2; POU1F1; PAX6; NOCT; ZBTB7B; PRDM2; ZNF432; ZNF253; HOXA2; NCOA1; ZNF696; LZTR1; MSC; ALX1; ZNF613; ZNF557; GCM2; ZNF208; NEUROG3; ZNF768; ZNF473; GSC2; LBX1; ETV2; ZBTB48; RAX; WNT4; ZNF813; FEZF2; NR0B1; MLLT1; CIR1; ZBTB6; PTTG1; CDK8; TBL1Y; HNF1B; ATF6B; SIX5; MLLT10; TCEA2; ZNF155; SUPT4H1; ZNF41; ZNF682; NR0B2; BCL11A; POU3F4; ZNF471; NFAT5; FOXN2; TLX2; GATA1; KMT2D; LMX1B; UTF1; PAX1; ZNF544; CEBPZ; KAT7; RFX1; SPIB; RHOA; SUPT5H; EYA2; SCAI; CRYM; NR5A1; RSF1; NACA2; ZNF674; ING4; TEAD3; ASCL2; MLXIPL; ZNF174; POU4F3; PITX3; CREM; MYB; HNF4A; EN2; NEUROG2; ZNF76; HOXD13; ZNF211; CBL; NR1I3; MAML1; ZNF692; HINFP; ZNF157; TAF6L; PIAS2; MAPK8IP1; MYEF2; HESX1; LHX5; NEUROD2; YEATS4; MYCL; PRDM8; HDAC9; EBF2; RXRA; SIN3B; ZNF79; HIF3A; KDM5C; FOXJ1; ZNF710; ZNF629; ALX4; CD3D; CSDC2; SIRT7; MEOX2; GLI1; ZNF287; BANP; MBD3; RXRB; HOXB3; SUB1; JAK2; MED15; ZNF215; ZNF493; SKIL; SKI; ZNF571; PGR; ZNF324; FOXJ2; ZNF80; SMARCD3; BRF2; RORA; TLX1; MED20; NFRKB; TXNIP; ZNF22; GLI3; MAFK; IKZF3; BACH2; ACTL6B; E2F6; SOX15; ZBTB25; ZSCAN2; GFI1B; RBL2; PIR; KLF3; GON4L; IRX4; TAF6; NKX2-5; RBFOX2; POU5F1B; ZNF665; ZNF646; ZBTB43; THAP9; ZNF74; FOXF1; ZNF219; ZFHX4; HMGXB4; ZNF528; GFI1; GLI2; ZNF787; UBP1; POU3F2; BCL3; USP16; PHOX2B; MYF6; BNC2; CERS4; KDM5D; PHOX2A; SOX10; NR1H2; ZNF770; CBFA2T3; PMF1; MNDA; ARID5A; PRDM12; ZNF589; SREBF2; CNOT2; AFF2; BRWD1; IRF8; TRIM24; AFF4; THAP10; LHX2; TP63; ERF; ZNF175; ETV1; HDGF; EN1; SREBF1; CREB3L1; MYRF; ASCL1; FOXE1; CBX4; EPAS1; FOXA1; ZNF117; TBX21; GTF2F1; SOX18; ZNF248; REPIN1; ELF3; ATN1; HLX; KLF1; SND1; HMGB2; TBX3; EGR4; ZBTB32; ZSCAN18; ZNF133; HLF; IRF6; PRMT2; ZNF45; PROX1; CBX5; FOXF2; LIMD1; NR1H4; EWSR1; SHOX2; NKX2-1; FEV; CREBL2; JUND; NANOG; RING1; ZNF331; SOX11; NFE2L2; HAND1; KLF9; POU2AF1; ZNF112; ZFHX3; MYT1L; TGIF2; CNOT3; TFDP2; RBPMS; PBX1; CBX6; TFEB; ARID4B; NFE2L3; MYCN; E2F8; RERE; LPIN2; HOXD3; CXXC1; ZNF574; ZNF24; TFAM; FOXG1; STAT4; TLE2; NFIC; BAZ2B; HOXC4; TSC22D1; ZNF580; VGLL1; RBPJ; SRF; HIC2; ARNTL; TRIM28; TRIM16; ZNF536; RARA; FOXN3; PLAG1; TDP2; BCL6; ETV4; NFE2; IRF4; MEIS2; HOXC10; ZNF350; IL16; SIX2; HIRA; STAT5A; ETV5; SAP18; ZNF532; PDLIM1; THAP11; SALL1; ZHX2; HOXB2; SMARCA1; AEBP1; ADRB2; CITED1; FOXD1; ZNF516; MED24; MSX1; CALR; GTF2I; NKX2-2; MKL2; ETS2; EHF; ERBB4; CTNNB1; YBX3; ID4; SOX9; FOXO1; ZNF423; SPDEF; RELB; SATB2; LEF1; TCF4; JUNB; SATB1; ZIC1; OSR2; CEBPA; SOX2; ABL1; E2F2
Down-regulation 168 LOXL2; TFDP1; MYBL2; ZNF593; GABPB1; HIF1A; JUN; NFKBIA; ELK3; FHL2; BIRC2; TLE1; ZNF32; ZMIZ1; FOSL1; RB1; USP22; TSC22D2; CBFB; XBP1; HOXA10; BRCA1; ZBTB11; MBD2; SIM2; YWHAB; TSC22D3; CBX3; PQBP1; KLF10; TOB1; RNF4; KLF6; PPRC1; MED17; HNRNPD; ELF4; CCNC; DACH1; NR2F2; STAT1; CARM1; SERTAD2; PSMC3IP; PREB; SP100; FUBP1; SOX4; SUZ12; HSBP1; ERG; HDAC6; BTAF1; GMNN; LMCD1; TAF1D; TBPL1; FOSB; RUNX1; RAN; ATF3; ZNF217; DNAJC2; FLNA; AHR; PTRF; SMARCC1; MTDH; RFXANK; DLX2; DR1; SFPQ; APEX1; NR2F6; BHLHE40; C1QBP; WWTR1; PCGF3; EGR2; NR2C1; DEK; DDX5; RBBP8; WWC1; BASP1; PMS1; CTR9; ID3; CEBPG; HSF2; TLE4; PRKDC; ZNF281; ID2; VEZF1; SMARCE1; EDF1; SNAI2; CTBP2; RREB1; ZFPM2; WT1; ZNF302; MECOM; VDR; CCNE1; NPM1; BAZ1A; SP110; ZNF512B; BATF; ETS1; MAFG; ENO1; ATF4; CTBP1; SMAD3; IRF1; ZNF91; CHD9; NFIB; PBX3; GATAD2A; ZBTB20; HOXB6; DMTF1; IFI16; CRY1; MAF; SMARCC2; CSDE1; ENY2; TAF12; RBBP4; KLF11; MYBL1; BHLHE41; HHEX; TBL1XR1; SCAND1; E2F3; KLF7; RCOR3; TCEB2; NFYB; FOXC1; HMGB3; ID1; KAT6B; ZFP36L2; SOX17; TOX; HTATIP2; TRIB3; STAT6; ZNF721; CUX1; NFATC3; GTF3A; RFX5; ZNF160; ZBTB38; TRIM22; EMX2; KLF4; GATA6; MEIS1; CREB1