Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08240 Withaferin-a GSE70138 HA1E Human 24h 1.11uM EID0010
Types Number Response transcription factors
Up-regulation 29 PAX8; FOXO4; NR3C1; ZNF23; ATF5; PEG3; RBPJ; NFYC; BANP; MAFG; GATAD2A; HOXD1; PIAS1; FOXD1; HSBP1; HTATIP2; NFAT5; CBFB; ATF3; ETV5; ZNF91; CITED2; NCOA3; HOXC6; NR0B1; TBX3; BBX; TRIP6; NFATC3
Down-regulation 59 NFKBIA; MYBL2; TP53; HDAC6; SOX4; HOXA10; MYC; FOXO3; HES1; FOXM1; ZMIZ1; NR4A3; PITX2; HIVEP1; SREBF2; APEX1; NFIL3; TGFB1I1; IRF1; ISL1; KLF10; WHSC1; ATF4; REPIN1; EHF; PDLIM1; ZBED1; BHLHE40; AEBP1; ZBTB18; TCF7L1; IRF4; EGR2; HOXA11; SPEN; HMGB3; EGR3; HOXB6; KLF6; LMCD1; ZFPM2; PITX1; NFE2L3; MEIS1; ZNF423; MEIS2; SMAD1; PBX1; ELF3; SOX11; FOXF1; TCF4; INSM1; DACH1; LEF1; CREB1; RELB; IKZF1; TBX2