Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08239 Withaferin-a GSE70138 HA1E Human 24h 3.33uM EID0010
Types Number Response transcription factors
Up-regulation 263 EGR1; FOS; HES1; ZNF195; ATF3; TAF4B; ZNF695; ID2; CHD2; ZNF232; FEZF2; ZNF225; ZNF682; ZNF223; ZNF701; FOSB; ZNF273; ZKSCAN8; TFAP2A; SOX13; TP73; ZNF235; FOXO4; IRF1; MAML3; ZNF154; ZNF222; SOX18; ZNF75D; ZNF586; EN1; ZNF304; ZNF155; HBP1; SOX17; ZNF415; ID1; ZKSCAN4; ZNF141; DDIT3; ZNF480; ZNF557; SIX6; SUPT4H1; NR4A2; ZBTB6; ZNF391; ZNF215; ZBED2; TBR1; ZNF423; ZNF34; NKX3-2; ATF4; ZSCAN9; HIC2; POLR3C; TRIB3; SKIL; ZNF606; DLX5; HESX1; THAP10; NFKBIB; CEBPB; MNDA; ZNF345; SCAI; TAF1A; TSG101; ZNF440; SRY; ESRRG; MED17; SMAD6; SUPT3H; RSF1; ZNF835; ZNF816; POU6F2; ZNF264; ZNF550; ZXDB; FOXE1; DLX2; ZNF214; PRDM10; SP4; ZNF675; GBX2; PRDM2; ZNF674; NEUROD1; CEBPD; ID3; VENTX; NPAS2; SIM1; ZNF80; TBX1; ZNF41; NHLH2; IKZF2; ZFP69B; ZNF81; HNF4G; L3MBTL1; ZNF35; ZNF780B; POU1F1; JAK2; MAK; HOXD1; MYT1; NR4A1; ZNF224; POU4F2; PAX4; CEBPG; THAP9; DMRT1; ZNF157; HINFP; ARNT2; NR1H4; ZNF227; CBX4; ZNF667; ZSCAN32; JUNB; ZNF407; YAF2; ZNF253; FHL5; HIRA; BNC1; ZNF132; ZNF239; ZNF10; JUP; HDAC9; ASCL2; ZBTB3; ZNF254; ATOH1; LYL1; TDP2; HAND1; CBFA2T3; CCNH; KLF4; HEY1; SOX3; ZIC3; PCGF1; HOXD3; ZNF394; SOHLH2; VPS72; NR2E1; TSHZ2; TBPL1; AFF2; HIPK2; ZNF654; HHEX; BARX1; CITED2; EGR4; CREM; ZFPM2; SOX15; VGLL1; ZNF165; NR5A2; TFEC; CBX7; SIX3; ZNF112; TWIST1; ZNF544; ZNF528; HLX; EMX2; LIN28A; ISL1; CUX2; PKNOX2; PIAS1; PPARD; NANOG; MECOM; ZNF593; ZNF175; KLF2; ST18; BRD2; ID4; ZNF331; MAFB; PEG3; EHF; C1QBP; MXD1; CAMTA1; IRF6; ZNF711; TDRD3; SMARCB1; PHOX2B; PQBP1; MAFF; FOXF2; CREB5; HMGA1; MEIS2; ZNF354A; POU2AF1; MYT1L; HOXD11; TERF1; ZNF467; GTF3A; ETV5; AEBP1; SPDEF; SSX1; TAL1; SALL1; MED21; MYCN; TGIF1; FOXG1; ZHX2; PAX6; EGR2; TSC22D1; PLAGL1; BCL11A; CRYM; MSX1; ZFP36L1; RBFOX2; OSR2; EGR3; SNAI2; NKX2-2; HLF; PBX1; TCF21; ZNF91; E2F5; ZIC1; SATB2; INSM1; IFI16; PPARG; BHLHE41; TRIM22; GATA2; SOX2; MEF2C; SOX9
Down-regulation 79 NFKBIA; CENPF; SMAD3; MAGED1; VEZF1; PRKDC; BCLAF1; NRIP1; MED1; WHSC1; PBRM1; WWTR1; FLNA; ENO1; SIAH2; NEDD8; KAT6A; MAF; ZBTB1; CNOT1; HDAC6; REPIN1; ZBTB38; ZNF148; HDAC1; CHD4; PURA; REST; NPAT; CENPB; PTRF; NFE2L1; SIX1; DDX5; AFF1; SMARCC1; YWHAB; ATF1; TBL1X; NELFB; CEBPZ; RAD21; EDF1; NFIB; PHF20; DMTF1; BRD8; RBL2; SFPQ; ASH2L; DNMT3B; HMGB3; FOXN3; BRD3; TFDP1; SREBF1; BAZ1A; SPEN; CSDE1; ERBB2; PBX3; NCOR2; CHD7; BIRC2; HOXC6; BHLHE40; IKBKAP; HOXA5; NR1D2; NKX2-1; TCF12; NFATC3; ZBTB18; BBX; STAT1; YBX3; PSIP1; KLF6; NR3C1