Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08238 Withaferin-a GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 769 NFKB2; EMX1; ZNF695; TBR1; CHD2; ZNF257; MAML3; FEZF2; ZNF235; ZNF701; ZNF75D; ZKSCAN8; NFKBIB; TP73; ZNF33B; E2F4; ZSCAN9; ZNF682; ZNF816; ZNF224; ZNF345; ZKSCAN4; ZNF180; ZNF141; NHLH2; ZNF155; MAK; NHLH1; ZNF232; PEG3; NEUROD1; SPI1; ZNF154; POU6F2; VENTX; PRDM14; ZNF362; NEUROD2; ZIC3; SOX13; ZNF391; MDM4; NR6A1; RFX1; ZNF195; ZNF343; ZNF124; TFAP2A; ZNF573; ZNF174; PRDM9; TAF1C; WHSC1L1; TAF4B; DOT1L; RBPJL; ZNF34; ZNF688; ZNF225; JUP; ZNF223; ZNF221; HSF1; BRWD1; ZNF273; ZNF440; RFX3; TCEA2; THRB; ZNF208; ZNF778; CDIP1; NR5A2; ZNF415; ZNF814; BCL11A; ZNF749; TULP2; SOX18; ATOH1; ZNF667; HESX1; SCAI; OVOL2; SRY; ZNF557; ZFHX2; FOXH1; TBX1; ONECUT1; ZNF471; SSX7; ZNF484; HSF4; NEUROG2; SOHLH2; HIC2; ASCL3; NKX3-2; NR0B2; TLX3; ZFP69B; HIPK2; NEUROD4; CIITA; SP4; HDAC9; PPARD; HNF4G; ZNF136; ZNF549; PRDM10; ZNF442; IKZF2; FOXE3; CDX1; ZNF423; JAK2; BRDT; GRIP1; POU2F3; ACTL6B; THRA; ZNF334; ZNF500; ESRRG; CEBPD; NR2C2; TULP1; NR5A1; ZNF254; ZNF132; SOX21; SCRT1; LHX3; ZNF264; MYF5; PRDM16; ZNF215; CBFA2T3; ZNF239; POU2F1; PAX4; ZNF480; NEUROG1; ZNF492; ZFP2; LIN28A; TBX6; ZNF780B; CARF; SOX5; ZNF550; NEUROD6; PIAS4; KLF8; HIF3A; SOX1; SIX6; SOX14; ZBTB44; EN1; HLX; ZNF81; ZNF214; L3MBTL1; POU4F2; HOXA3; PRDM12; NANOG; UTF1; HOXB8; MLLT1; ZNF93; MAPK8IP1; ZNF74; ZNF80; ZIM2; ZNF157; ATF7; ZNF606; SOX17; ALX4; ZNF675; ZNF674; PRDM2; ZNF287; POU4F3; GTF2A1; NR1H4; ZNF234; ZNF8; ZNF142; PAX7; ZNF304; ZNF696; ZNF222; ETV3; VGLL1; ZNF835; PRDM5; SNAPC4; ZNF117; MDM2; NEUROG3; ZNF407; ZNF41; FOXD3; ST18; VHL; IKZF3; ZNF43; SSX3; ZXDC; ZXDB; HOXD12; CBX7; PPARA; HES2; ZNF507; POU3F3; PAX1; E4F1; ZNF544; ASH1L; PAXBP1; TAF5; ZNF586; BNC1; TONSL; ZNF536; FOXB1; ZBTB3; ERBB4; FOXL1; ZNF135; ZNF10; GBX1; GCM2; ZNF669; GBX2; NOCT; TLX2; ZNF671; CRX; HMX1; TBL1Y; GCM1; FOXN2; ZBTB39; TEF; ARHGAP35; ZNF85; GSC2; DLX5; TFDP3; HEYL; SOX3; ZBTB6; AIRE; ZNF623; ZNF354A; ARID3A; POU1F1; ESR2; ZFP37; MSX2; LHX1; MYT1; MYEF2; PDX1; HOXC5; CDX4; CBX8; TFEC; PRRX1; ZFHX3; IRF6; FHL5; POU5F1B; POU6F1; LBX1; RORB; SHOX; ZKSCAN3; NFATC4; PAX6; ZFY; ZIC4; ZNF79; SUV39H2; POU2AF1; CUX2; TAF1A; ZBED2; YBX2; ETV2; LMX1B; ALX3; ZNF613; DLX6; HOXB1; KLF15; ZNF665; DCC; TBX5; HINFP; ZSCAN2; ZNF350; NKRF; PROP1; FOXE1; ZNF202; AFF3; RXRG; ZNF44; SOX30; RARG; ZNF35; NACA2; BARX1; THAP9; NKX6-1; SOX12; ZNF324B; ZSCAN32; TWIST1; PAX3; ZNF165; TAF5L; ZNF286A; MYCL; ZNF551; ASCL2; HOXA2; NFIX; RFXAP; CNOT3; TCF21; RORC; OVOL1; DMRT1; ELK4; TRIB3; MED31; CEBPE; ZNF467; HOXA6; AFF2; SAFB2; ZNF446; TAF6L; NPAS1; SAFB; SHOX2; ESRRB; NRL; HNF1B; KMT2D; ZNF227; ZBTB17; SALL2; EYA3; HOXC11; REL; CAMTA2; ZBTB7C; SKIL; ATF6B; CBX4; TFAP4; GON4L; PAX2; TLX1; POU3F4; ZNF460; PKNOX2; SP1; VDR; SMARCB1; CCNT1; HIC1; TSHZ2; LYL1; ZFPM2; ARID3B; HNF4A; THAP10; ZNF639; CBFA2T2; KDM5C; ZNF770; ZNF253; PML; ZNF711; VSX1; ZBTB20; TAF1; NKX2-5; FOXJ1; ARNT2; VAX2; MNX1; MYNN; ZNF529; HMGXB3; SKI; OLIG2; NFE2L2; EPAS1; ZNF219; PRDM1; BAZ2A; RSF1; RORA; AR; NAB2; ZNF771; ZNF112; GRHL2; IKZF4; PCGF1; TBX4; MEIS2; CEBPG; ZNF248; LZTR1; MXD3; DLX2; CBL; PRDM8; TCF7L2; PITX3; HDAC4; FOXC2; TGS1; HNF1A; PROX1; ZNF493; HBP1; PAX9; LHX2; ING4; ZNF335; ONECUT2; ZNF250; CBX2; KLF13; POLR3F; STAT2; ZNF205; LDB1; POLR3C; CDX2; SSBP3; FOXD2; SIM1; SIX3; TBX19; MZF1; FOXI1; MED12; ZBTB48; ZBTB7B; HOXB5; ZSCAN16; HIVEP3; TFDP2; NR2E1; GMNN; ZNF528; RAX; STAT4; ZNF556; PHF8; HMGA1; FOXF2; PRMT2; ETV7; MYBBP1A; TFAP2B; IRF1; THAP3; FOXN1; ZNF175; EMX2; MXD1; INSM1; KLF3; ZNF133; MECOM; SMARCA4; NR3C2; HMBOX1; SPDEF; ETV6; MECP2; TRIM33; LHX5; ZNF426; SALL1; PRDM13; GATA1; ZKSCAN7; THAP7; POU3F2; TUB; SETDB1; ZNF506; FOXM1; FOXP3; TAF7L; HOXD1; ZNF91; KAT2B; CCNH; ZNF14; CRYM; INSR; FOXJ2; MNDA; KAT2A; EP300; ARID5A; CBX6; ZNF331; GCFC2; MAP3K10; ERCC3; NKX2-8; BARX2; ZKSCAN5; EGR1; ZNF611; EHMT1; FOXA2; KLF11; ZNF768; HHEX; CSDC2; HEY1; GLI2; ZNF668; RFX2; HAND2; ZNF562; TAL1; ZFP30; ZNF23; FOXA1; HOXD13; IFNB1; MED25; ZSCAN12; ZNF710; ZNF444; ZHX3; EBF2; CD3D; ZNF646; MYOD1; ESRRA; EHMT2; ZSCAN31; TDP2; KAT6B; ZNF764; SOX15; HOXC4; HES1; TLE2; LHX6; MYOG; ZNF324; HLF; ZBTB7A; GMEB1; ZNF329; TDRD3; PBX2; ZIC1; SMAD9; NR1I3; SSX1; MYT1L; FOS; FOXG1; ATN1; FEV; TTF2; ARRB1; SUPT7L; MAFK; NFE2; ZNF654; ZBTB16; MED17; NR1I2; RBL2; CIR1; YEATS2; IRX4; DYRK1B; ASCL1; ZNF432; TERF2; ARL2BP; SUPT3H; TEAD3; TGIF2; C1QBP; TFAP2C; UBTF; MEF2C; MYCN; ID1; DLX4; JUN; MAFB; IRF8; ZNF3; WNT4; ZNF268; PKNOX1; NFAT5; HOXD3; SUPT5H; MYB; ZNF571; ATF3; MAFF; HIRA; CAMTA1; SIX5; BNC2; GFI1B; PHIP; HDAC5; CRTC1; ZNF589; SOX11; EN2; ESR1; NFX1; MEF2D; PHF1; PNRC1; MTF1; ZNF512B; HOXB2; ISL1; CREM; TCF7L1; TAF11; ZBTB43; ZNF430; KDM4C; MKL1; PEX14; HAND1; RFX7; GFI1; PGR; ZNF692; ZNF394; MAFG; HOXA4; TRPS1; VPS72; ZFP36L2; PLAG1; BLZF1; KMT2B; AEBP1; SRCAP; SPIB; FUBP1; E2F8; CREBL2; MTA2; ARID1A; TRIP11; SUPT4H1; TCF3; NR0B1; ZNF107; POLR2A; KLF4; SP140; PAX5; NPAS2; ZNF45; YEATS4; ZNF552; TBPL1; NR4A1; TSC22D3; PPP1R13L; ZNF574; PHOX2B; ZNF813; CAPN15; NCOA2; ELF3; HEY2; RBBP5; SOX2; RING1; TEAD4; ID3; PIR; BANP; CALCOCO1; IRF9; AGO2; SNAI2; TP63; ZBTB32; ZNF200; TRIM24; DACH1; PIAS1; FOXF1; NR1H3; ELF4; MEOX2; WT1; SATB2; NKX2-1; PLAGL1; ETV1; BCL6; NFE2L3; TULP3; TOX; ZSCAN18; ZNF652; SOX10; TFCP2; ETV5; FLI1; ZHX2; TERF1; BRD4; RYBP; NR2C1; TCF4; DDIT3; KLF1; ERG; BACH2; OSR2; FOSB; NCOA3; NR2F1; NKX2-2; IKZF1; GATA6; RFX5; GATA2; JUNB; EHF; NR1H2; ZNF721; TOX3; TRIM22; ID4; E2F2; TBX2
Down-regulation 155 RHOA; ATF6; LOXL2; SMARCA5; MAGED1; ECD; TCERG1; EDF1; HDAC1; BCLAF1; ENO1; HNRNPD; CCNA2; NFE2L1; FOXJ3; NCOA4; CENPF; MYC; ATF1; FHL2; HDAC2; NEDD8; SMAD2; NUP62; BASP1; TAF10; VEZF1; SUV39H1; TP53; DDX5; PUF60; BHLHE40; UBE2I; RNF10; PAX8; RNF4; CRY1; EZH2; REST; YWHAB; RUNX1; SMARCC1; RB1; CTR9; BRD8; HOXC6; MED13; LPIN2; SIAH2; JARID2; ING2; ZBTB38; HDAC3; RFC1; SETD2; PBRM1; RBBP4; NRIP1; BMI1; USP22; NPAT; TAF7; GTF2A2; RBM39; NCOR2; PREB; ZNF146; HOXA10; BRD3; FLNA; TRIM32; ZBTB11; IKBKAP; TCF12; ARID4B; WHSC1; CHD1; ZEB2; NCOA6; SMARCE1; SND1; PMF1; NR2F2; NONO; SMAD3; PRKDC; ZBTB18; STAT3; DEK; RAN; YBX1; ATF4; NRBF2; ZBTB1; PSMC3IP; DNAJC2; SFPQ; HOXA5; SIX1; MTDH; ELK1; RBM14; USF2; GTF2IRD1; SP3; TBL1XR1; SCAND1; KDM2A; PIAS3; PSIP1; SUB1; BAZ1A; TCFL5; ARNTL2; NAB1; SMARCA2; BAZ1B; IRX5; AFF1; BIRC2; SPEN; EGR2; ITGB3BP; CBX3; RBBP7; KLF10; MED1; BLM; TSC22D2; HMGB1; SSRP1; SREBF1; PHF20; CREB3L1; REPIN1; SMAD4; ELK3; RNF6; TBL1X; BCL11B; KLF6; FOXC1; DMTF1; HLTF; BRCA1; KLF5; WWTR1; ELF1; TRIP6; TLE4; HOXC10; HMGN3; PBX3; TRIM16; NR3C1