Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08237 Mitoxantrone GSE70138 HA1E Human 24h 0.04uM EID0010
Types Number Response transcription factors
Up-regulation 124 CEBPD; ZNF274; ZNF432; ZNF223; DMRT1; THRA; RHOA; TRIM22; TP63; PBXIP1; BNC1; ZNF227; TFEB; FOXE1; HOXB13; PAX6; OLIG2; AR; ZNF692; HCFC2; SSBP2; ZNF614; ZNF205; TTF1; TFEC; CDC5L; BHLHE40; ZNF226; SOX9; PLAGL1; ZNF112; MED15; NCOA4; ZNF195; ZNF337; ZNF571; THAP10; ARNTL; MYRF; CALCOCO1; MAGED1; ZNF529; SIX3; TRIM16; MNDA; ZNF468; PDLIM1; NR1H3; IFI16; MEIS2; NFIL3; ZBED2; ARRB1; SMAD5; WWTR1; EYA2; RNF141; NR2E1; RSF1; PITX1; CD3D; MDM2; HOXA1; NPAS2; BRF2; SOX15; YAP1; ZNF350; SHOX2; TFCP2; LHX2; ZNF282; SIX1; ZNF133; MAFF; IRF5; NEDD8; ZNF410; ZNF268; ZKSCAN1; PPP1R13L; GRHL2; TLE2; IRF9; MNAT1; CRY1; SSX1; HLX; TEAD3; PIR; SMARCA2; FOXG1; KLF5; NR0B1; CERS4; RBBP7; POU4F1; NKX2-2; FOXA2; TRIP6; CITED1; IRF8; TWIST1; IKBKAP; LITAF; NR1H2; ATF3; TFAP2C; ETV5; SUB1; NFIB; ELF3; SMARCA1; BHLHE41; HOXB2; GATA6; RXRA; TXNIP; TBX3; YBX3; SOX11; ETV1; ADRB2; RELB
Down-regulation 126 GMNN; CCNH; CCNA2; ARID5B; HOXA10; HNRNPD; TGIF2; GABPB1; USP22; VEZF1; UBP1; CBX3; ZNF217; CNBP; CENPF; YWHAB; GATAD2A; TBL1XR1; SMARCC1; NFATC4; SAP130; ZMYM2; POU5F1B; SMARCE1; ZNF652; HMG20A; FOXM1; HMGB2; ZNF423; BRD7; TFDP1; PQBP1; ELF4; LMCD1; TCF3; LIN28A; MECOM; WWC1; NPAT; TBPL1; KAT6B; BRCA1; MED4; DACH1; CTCF; THAP4; XBP1; DNAJC2; ZFP36L2; ZNF24; TAL1; PHIP; SMAD6; PURA; CHD1; FUBP1; SP100; RYBP; ZMIZ1; ZHX2; FOXN3; EGR1; MAZ; MBD2; RREB1; PTTG1; ENO1; SCAND1; AGO2; GTF3A; PPARGC1A; E2F3; PATZ1; ZMYND8; HIPK1; NR2F6; PHF1; TLE4; HHEX; HOXC10; ZBTB20; KLF2; BCOR; NR1D2; ZBTB38; UBE2B; NR2F2; PHF20; HOXB6; ERG; HOXA11; NFE2; ID4; ZBTB18; ID1; TBL1X; HMGB3; CREB3L1; RBBP8; ZNF721; ID3; RERE; MTF2; CTBP2; AEBP1; SFPQ; KLF11; ZFPM2; TOB1; CARHSP1; ZEB1; HOXC6; HLTF; CREB3L2; NFATC3; ZNF160; CITED2; MYBL1; SMAD1; ARNT2; ESR1; CREB1; THAP11; BBX; SNAI2; GATA2