Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08236 Mitoxantrone GSE70138 HA1E Human 24h 0.12uM EID0010
Types Number Response transcription factors
Up-regulation 35 TRIM22; MDM2; PEG3; TRIM29; TP63; CDIP1; MAF; DDIT3; ZKSCAN1; ZNF432; CEBPB; ZBTB43; HMGA2; ATF3; ETV5; PDLIM1; RORA; SP110; FOS; TSC22D2; SMARCA2; TOB1; IRF7; IRF9; SOX9; KLF5; ZNF91; YBX3; NFIB; KLF4; TBX3; HTATIP2; RXRA; AHR; PBX3
Down-regulation 48 CCNA2; MYC; CENPF; PARP1; ARID5B; HMGB2; PTTG1; UBP1; HNRNPD; SOX17; YWHAB; MAZ; HCFC1; AGO2; VEZF1; PITX2; TBL1XR1; MBD2; BCLAF1; ID4; SSBP3; SMARCC1; HOXB7; E2F8; MLXIP; E2F5; MYBL1; NR2F6; RHOA; AEBP1; BLM; ZHX2; ARID1A; NR2F1; CHD7; CALR; CUX1; GATA6; CREB3L2; MECOM; THAP11; TBL1X; WT1; ASCL1; ZBTB16; HEY1; SATB1; TBX2