Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08235 Mitoxantrone GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 217 TP63; DAXX; EGR2; TRIM29; MAF; ZKSCAN1; TCEA2; ZNF140; TRIM22; ZNF79; IRF9; ZNF264; ATF3; ZKSCAN5; BCL6; CDIP1; ZNF74; BNC1; ZNF223; CEBPB; NHLH2; ING4; ZNF211; MDM2; CERS4; SOX4; MNT; DMRT1; SOHLH2; PRDM1; SSX1; ZNF266; CBX7; TWIST1; ZNF692; ZNF195; ZNF394; ZNF430; ZNF14; TBX1; RORA; ZBTB43; EGR4; SETDB1; ZNF226; IRX4; ZNF337; CALCOCO1; ETV5; AR; SIRT7; CREBL2; CUX2; FOXE1; TRRAP; PHF8; CREM; SUPT4H1; ZNF557; ZNF225; HLX; THAP10; ZNF682; DDIT3; ZNF529; ZNF304; GATA3; BHLHE40; SOX15; ZNF432; ARNT; HABP4; PBXIP1; TAF11; ZNF212; PCGF2; ZNF134; ZNF419; SNIP1; CAMTA2; L3MBTL1; CREG1; ZSCAN32; ZNF141; ZNF273; ZNF415; ZSCAN31; SMAD5; HCFC2; ZNF222; ZNF23; BHLHE41; ZNF426; NR0B1; IFI16; STAT2; SUPT7L; ZNF268; ZNF136; NFIX; RING1; BRDT; CBX6; ZNF227; PIR; TTF1; HBP1; PDLIM1; PCGF3; FOXA1; PAX9; ZNF354A; ZNF45; RNF14; PNRC1; CITED1; TAF7L; TRIM16; ZNF571; RRN3; SOX9; KLF4; ZNF112; HINFP; HOXA1; ZNF133; SIX3; PPP1R13L; RUNX3; KLF5; ZNF43; IRF6; ZNF200; RSF1; BRF2; HLF; HIRA; KLF11; MED13; GFI1; EGR3; ZNF267; RBL2; MED20; FOSL1; AHR; ZNF184; SHOX2; ARID5A; ZNF107; SAP18; ZNF532; ARNTL; TAF9B; STAT1; TGIF1; ZBED2; ZNF282; LHX2; MED15; STAT4; TBX3; ZNF117; ZNF12; NR2E1; SNAI2; TFEB; JUNB; IRF1; TDP2; TSC22D3; ZNF350; YAP1; ZNF468; FOSL2; ZNF91; NRBF2; ETS2; OLIG2; IRF8; SMARCD3; TRIB3; FOXF2; ST18; RCOR1; GATA6; TLE2; TRIP6; PAX6; BCL11B; KDM5D; OSR2; NFIB; FOXG1; ZBTB16; MITF; BCL3; NKX2-2; JUP; TXNIP; SP110; ZFP36L2; NR1H3; TSC22D1; YBX3; NR4A2; PBX1; NKX2-1; TOB1; NFE2L3; SOX11; ELF3; MYRF; RXRA; ADRB2; NR1H2; MEF2C
Down-regulation 121 TLE1; CCNA2; MYBL2; CENPF; HNRNPD; MYC; PARP1; PAX8; HMGB2; SMARCC1; NFATC4; ATF6; FOXM1; AGO2; STAT5B; TFDP1; XBP1; VEZF1; BRCA1; HOXB6; NR2F2; CCNH; MLX; CREB3L1; BCLAF1; UBP1; PPRC1; RBM39; CHD7; BAZ2B; WWC1; USP22; MLLT10; SFPQ; HOXB7; KLF2; TGIF2; ENO1; SMAD1; CARM1; MAZ; HDGF; CALR; ZNF148; PA2G4; KLF6; ZMIZ1; ZZZ3; SMARCB1; E2F8; KLF7; NPAT; TBL1XR1; CHD9; CNOT1; ERG; SF1; MTDH; TGFB1I1; WHSC1; SUPT3H; TLE4; TBL1X; CBX5; BRIP1; CBFB; MEF2A; CBX3; PRMT2; ETS1; GATAD2A; CTBP2; TCF12; IRX5; YWHAB; MBD2; ZBTB1; BLM; CCNE1; ASCL1; NR2F6; HOXB5; CREB3L2; KMT2A; DNAJC1; FLNA; ID3; RAD21; ZNF423; RBM14; ATF4; RNF138; CUX1; NCOA1; CSDE1; HIPK1; BRD7; SALL1; FOXC1; MECOM; BBX; ESR1; ZHX2; ID4; ZMYND8; ID1; TCF21; ZBTB18; MYBL1; SPEN; HMGB1; SOX17; NFATC3; MNAT1; CARHSP1; SMARCA1; THAP11; AEBP1; CREB1; SATB1; GATA2