Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08226 Chir-99021 GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 77 SOX4; FOXO3; PAX8; ZNF195; TCEA2; JUN; CTR9; DEAF1; HDAC3; SOX17; TSC22D1; PRKDC; HOXA10; PRDM2; ING4; RFXANK; GLI2; HMG20B; DLX4; SCAND1; CIR1; CBX6; TSC22D3; ID1; ZNF264; SALL1; APEX1; TGIF2; DLX5; CBX5; NAB2; ATN1; ZNF423; SSBP3; SRCAP; TRIM28; ARNT2; ZNF611; MAZ; ZBTB20; ZNF629; SOX9; ZFHX4; BHLHE41; TERF2; BNC2; CUX2; ELF3; CERS4; ZNF711; INSR; SOX11; MSX1; ESR1; BCL11A; TCF7L2; AR; ARID1A; CBFA2T3; MTF2; FOXG1; ZNF160; FOSB; ZMYND8; VGLL4; AEBP1; ZFP36L1; MNDA; ZNF721; IRF8; EMX2; TCF4; HOXC6; MAFB; SATB2; NR2F2; THAP11
Down-regulation 37 CCNA2; XBP1; ZEB2; GMNN; ARID5B; PEG3; DEK; SMAD2; NFIL3; TMF1; ATF1; STAT3; PTTG1; KAT2B; TOX3; SOX10; FOXD1; ELF5; HMGB3; JARID2; SAP30; LMCD1; TP63; MYBL1; MNAT1; CREB3L1; TRIM29; ZEB1; SP110; KLF2; KLF9; TXNIP; BBX; CITED2; GATA6; TOX; BTG1