Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08207 Torin-1 GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 80 NFKB2; MYC; ZNF33B; HMGA2; KLF13; TCEA2; ZNF688; TGFB1I1; MTA1; ARID5B; EZH1; ZNF623; ZNF573; ZNF423; NEUROD1; SPI1; HDAC9; SNAPC4; CIZ1; MAFF; HMGA1; APEX1; HDAC5; HBP1; INSM1; JUP; MEOX2; ZNF239; CNBP; FOXN3; FOSL1; WHSC1; SCAND1; BRD3; ZNF302; CEBPB; EPAS1; ZNF264; LYL1; ZBED1; TULP3; SMARCB1; PPARD; RELB; ZNF232; SMAD3; KLF6; ZNF91; DLX5; HOXD1; GTF2IRD1; TWIST1; EDF1; DLX2; ZFPM2; KLF5; TAL1; PMS1; ID4; KLF11; ST18; FOXG1; ARNT2; YBX3; ERG; ZEB1; EMX2; HHEX; FOXD1; KLF4; ID1; HOXA5; ID3; ZBTB16; SOX11; AEBP1; SNAI2; MAFB; NFATC3; ABL1
Down-regulation 25 MYCBP; GTF2A2; IRF4; NFIL3; IRF2; BHLHE40; MAGED1; UBP1; CCNC; EGR1; XBP1; ZEB2; SIAH2; NKX3-1; STAT3; YWHAB; SUB1; SERTAD2; PIR; MNAT1; CREB3L2; SMARCA1; GATA6; THAP11; TBX2