Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08205 Torin-1 GSE70138 HA1E Human 24h 3.33uM EID0010
Types Number Response transcription factors
Up-regulation 140 MYC; HSF1; TCEA2; ING4; EZH1; ZNF34; ZNF33B; ZNF623; HMGA2; MAFF; SNAPC4; ZNF232; ZBTB48; INSR; ZNF358; ZNF345; MDM4; TWIST1; HES1; HDAC9; HBP1; ZNF667; HDAC5; TBX1; ZNF219; SIX6; ZNF239; KLF13; ZNF500; FEZF2; L3MBTL1; ARID5B; RXRG; SOX17; THRB; LHX3; ZBTB25; MTA1; ZNF93; PAWR; HINFP; BCL11A; DLX4; ZNF133; NFATC4; HOXB13; ZNF593; SOX18; ZKSCAN7; NFE2L1; HOXB7; CREBL2; KLF11; ZNF43; TGFB1I1; DLX5; ZNF573; PRDM2; SALL2; LZTR1; BTF3; PFDN5; LHX6; CBX4; MZF1; ZNF282; ZNF415; NR1I2; GTF2F1; NEUROD1; SOHLH2; NPAS2; SOX13; SIX3; PHOX2A; ZNF532; CALCOCO1; ETV4; TLE2; HOXC4; CBX7; ZNF536; HOXB5; ZBTB16; ZNF354A; ATN1; TFEB; SKI; MYT1L; JUND; ZSCAN16; CEBPB; ZNF32; LYL1; NFE2L3; TAL1; ZNF302; KLF7; ZBED1; ZNF165; ZNF711; PBXIP1; ZNF529; ARNT2; HEY2; BRD4; ZNF83; TCF7L1; CERS6; PHOX2B; REPIN1; COPS2; ZNF580; TRIP6; SSBP3; ZSCAN18; TGIF1; HMGA1; ETV5; MXI1; FOXA2; IRF6; STAT6; EMX2; ESR1; ZNF423; CTNNB1; AEBP1; PAX6; ERBB4; TCF7; PAX5; INSM1; IFI16; SPDEF; HTATIP2; FOXG1; ZIC1; MEF2C; ABL1
Down-regulation 63 MYCBP; MAGED1; ZSCAN5A; NFIL3; GTF2A2; BHLHE40; MAF; CCNA2; SUB1; NFKB1; NCOA1; ATF1; EGR1; NR2F1; PEG3; XBP1; MEF2A; CENPF; EGR2; SMAD5; PLAGL1; STAT3; SFPQ; NFAT5; PTTG1; PTRF; NR4A3; ZNF124; RNF111; ZBTB18; MBD2; RNF138; RCOR1; TRIM29; TRIM16; RYBP; CREB3L2; TOX3; YWHAB; TGFB1; CREB3L1; NFATC3; BBX; FOXC1; HLF; KLF5; PIR; SOX9; NKX3-1; ZBTB38; OSR2; NR2F2; LITAF; ZFP36L1; EGR3; TOB1; HMGB1; TXNIP; MYBL1; FOXF1; SNAI2; CREB1; TBX2