Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08204 Torin-1 GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 128 HES1; MYC; ZNF224; TGFB1I1; ARID5B; EZH1; ATF4; PPARD; HDAC5; TRIB3; CEBPB; PIAS4; TCEA1; CAMTA2; CEBPD; HBP1; ZNF551; ZBTB48; MAFF; E4F1; KLF7; HOXD1; ING4; TWIST1; MAFG; CBX7; NPAS2; L3MBTL1; CALCOCO1; ZNF264; PRDM4; ZNF573; ZNF623; HMGA2; NEUROD1; PCGF1; ZNF232; ESRRA; INSR; HOXC4; HMGA1; HDAC6; CBFA2T2; PCGF3; HDAC7; TDP2; MTA1; ZNF394; SETDB1; CDK7; KMT2B; ZNF211; ZNF532; CXXC1; KLF13; GTF2F1; TAL1; CIZ1; ELF3; ZNF117; SSBP3; ARNT2; INSM1; PPP1R13L; HDAC9; FOXN3; EP300; ZNF354A; PAWR; DLX2; DDIT3; DLX5; ZNF611; COPS5; SMARCC2; TEAD3; ETV4; TERF2; ERG; TCF7L1; LMCD1; ZFP36L2; CBFA2T3; KLF5; AEBP1; UBE2B; EMX2; KLF2; HOXB7; ZNF83; ZNF217; MXI1; STAT6; ZNF160; IRF8; ST18; ZFPM2; MYRF; MYBL1; RERE; KLF11; JUP; ZNF721; FOXO1; FOXG1; ZNF91; ATF3; RUNX3; PAX6; FLNA; STAT4; ERBB4; IRF6; DACH1; MYB; TGFB1; PAX5; ID4; MECOM; BACH2; HOXC6; KLF6; YBX3; SPDEF; SOX11; ESR1; THAP11; ABL1
Down-regulation 68 MYCBP; PAX8; ATF6; NFKBIA; PARP1; GTF2A2; CCNA2; BHLHE40; PIAS2; MAGED1; ECD; NFIL3; CCNC; SUB1; SIAH2; IRF4; SMARCA5; HOXA10; HMGN3; NUP62; TRIM29; PIR; NCOA4; PEG3; NFKB1; ATF1; ENO1; ZMIZ1; HIPK3; THAP1; ING2; HNRNPD; PITX2; REST; ZBTB38; CDYL; MYCN; TRIM16; MED21; EGR1; MTDH; XBP1; PTTG1; EGR2; SFPQ; STAT3; HOXA11; SIX1; ZBTB11; RBBP7; ASCL1; ZNF267; BATF3; CITED1; SMAD5; PDLIM1; TP63; TBL1X; ILF2; BMI1; MITF; MNAT1; EGR3; HLTF; ID2; TOX; TXNIP; TBX2