Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08197 Gsk-2126458 GSE70138 HA1E Human 24h 0.04uM EID0010
Types Number Response transcription factors
Up-regulation 137 TCEA2; FOXO4; SOX4; HBP1; MNT; HDAC5; CBX7; ING4; HMG20B; ZNF33B; SIX6; CEBPZ; ZNF223; CEBPD; FEZF2; RSF1; PPARD; HDAC6; PBX1; SETDB1; ZNF227; BPTF; ZNF337; ZNF415; ZNF117; ZNF141; ZNF232; ZNF358; ZNF219; ZNF225; EZH1; CALCOCO1; ZNF112; RBPMS; SIX3; ZNF74; LZTR1; SIN3B; ZNF195; ZIC3; FOXN3; ZNF334; ZNF133; EZH2; PCGF3; ZNF345; MYCL; IFI16; NONO; ZNF835; ZNF623; SOX13; ZNF136; TTF1; PNRC1; SALL2; PPP1R13L; RING1; PAXBP1; ZBED1; FOXG1; ZNF665; ZNF264; TBX19; NLK; NANOG; CREBL2; ZNF528; PFDN5; ZNF394; TRIM22; ZNF91; CDIP1; ZNF43; ARID4B; PRMT2; GLI3; PBXIP1; TCF25; CXXC1; STAT4; ZNF302; MTA1; MAFF; SMAD2; LHX2; ZNF83; HOXA10; BAZ2B; PCGF2; VPS72; ZNF146; MEOX2; KLF11; HMGXB4; ST18; TFAP2C; TWIST1; IRF6; TLE2; MSC; SOX11; HOXD1; HOXB2; TGFB1I1; INSR; SP110; CUX2; RERE; RNF141; HEY2; BCL3; LIN28A; ZNF532; TFEC; TGIF1; PLAGL1; STAT6; SPEN; BCL11A; NCOR2; TBX3; MNDA; FOXO1; ELF3; KDM5D; TRIP6; SATB2; NFE2L3; MYRF; PSIP1; NR1H2; HOXA5; TCF4; SPDEF; CREB1; ABL1
Down-regulation 49 TLE1; NFKBIA; PAX8; XBP1; AGO2; YWHAB; ENO1; TFDP1; YAF2; MXD4; GATAD2A; NRIP1; SFPQ; MTDH; LEF1; USP22; NFIL3; MAF; ETS1; RNF111; RAN; YBX1; FOXC1; MEOX1; PTTG1; NR2F2; WWC1; C1QBP; PSMC3; BRD2; ATF1; EGR3; TBL1XR1; ELF1; CHD7; RNF6; FLNA; NR4A2; TOB1; NFATC3; MTF2; MYCN; ZBTB18; DACH1; HMGN3; SNAI2; WT1; MEIS1; TBX2