Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08196 Gsk-2126458 GSE70138 HA1E Human 24h 0.12uM EID0010
Types Number Response transcription factors
Up-regulation 162 TCEA2; SETDB1; FOXO4; HBP1; SOX4; ZNF219; ZNF688; ING4; MXD3; CEBPD; POU2F1; HES1; HMG20B; HDAC5; MZF1; HSF4; EZH2; RBPJ; PCGF3; ZNF358; FEZF2; VPS72; TTF1; HOXB7; HOXA7; FOXM1; SIX6; CARM1; PFDN5; THRA; PPARD; BPTF; PCGF2; NHLH2; HDAC6; ZNF205; TGFB1I1; PMF1; SSBP3; ZNF430; ZNF74; KLF13; PBX1; ZNF195; MYCL; PIAS4; KLF11; JUP; EZH1; ARID4B; APEX1; CALCOCO1; CBFA2T2; ZNF264; ZBED1; TCF7L2; ZIC3; NONO; TCF25; AES; KMT2A; HDAC4; PNRC1; HIPK2; STAT2; SMARCB1; MED14; CBX7; DBP; ZNF580; KMT2B; ATN1; TGIF1; GFI1; MTA1; POU4F1; PPP1R13L; FOXG1; ZNF423; AIP; HOXA10; ZNF266; YEATS4; INSM1; SMAD7; MED24; ARID1A; RSF1; CXXC1; CNOT2; HOXA11; NR0B1; INSR; ZNF544; IRF3; BCL11A; ELF3; HOXD11; UBE2L3; ZNF232; HOXC4; TRIB3; ZNF117; ZNF467; HOXB5; TULP3; PBXIP1; ZMIZ2; WNT4; SOX11; ZNF532; IRF6; RING1; TBL1X; SAP18; ZNF22; HOXD10; MED15; STAT4; ZKSCAN1; PAX5; CD3D; DLX5; SIX3; SCAND1; RNF141; ST18; HMGB3; CERS6; COPS2; EMX2; ARNT2; TERF2; TFCP2; POU2AF1; ARNTL2; HMGA1; AEBP1; BACH2; HEY2; SMAD1; EYA2; BTG1; SATB2; FLI1; YBX3; MYRF; ERBB4; OSR2; NR1H2; RBFOX2; KDM5D; TCF4; MNDA; IFI16; SOX9; HOXA5; HOXC6; MAFB; SATB1; SPDEF; ABL1
Down-regulation 52 NFKBIA; XBP1; PAX8; ENO1; EED; UBP1; SFPQ; WDR77; NFIL3; TFDP1; YWHAB; HNRNPD; TSC22D2; CCNH; CREB3L2; GATAD2A; FOXC1; MTDH; HSBP1; ETS1; USP22; PURA; DMTF1; LEF1; CCNC; ELF1; ATF1; ZBTB38; MAGED1; HIPK1; STAT3; HMGN3; NR2F2; RAN; MITF; CITED2; PBX3; SOX10; BMI1; AFF1; TRIM24; BBX; WT1; ASCL1; NR4A2; MYBL1; AHR; ATF3; TBX3; SNAI2; THAP11; TBX2