Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08195 Gsk-2126458 GSE70138 HA1E Human 24h 0.37uM EID0010
Types Number Response transcription factors
Up-regulation 139 TCEA2; FOXO4; SOX4; ZNF33B; ING4; CEBPD; HMG20B; HDAC5; ZNF500; SETDB1; EZH1; HES1; EZH2; PCGF3; USP21; CBX7; CEBPB; ZNF573; TTF1; ZNF345; ZNF117; TCF25; ZNF264; HBP1; CALCOCO1; ZNF195; ZNF358; CREBL2; FEZF2; ZNF74; ZNF219; ZNF586; PNRC1; GTF2F1; MTA1; LZTR1; ZNF85; PBXIP1; CDK7; KLF13; ZNF226; TCF7L2; FOXG1; THAP10; ZNF430; LHX2; ST18; SIN3B; HMGB3; MZF1; MEOX2; NR2E1; ZNF544; ZNF536; BRD3; APEX1; ZNF43; ZNF83; TGFB1I1; PPARD; PCGF1; ZKSCAN1; MAFF; AES; ZNF32; HOXA10; TGIF1; ZNF45; PFDN5; ZNF432; TBX19; ZNF112; KDM5D; PAX6; ZBED1; ZNF22; ZNF529; ZNF354A; ZNF232; RSF1; KLF11; RXRA; ZNF91; VGLL4; MNDA; EP300; INSR; PCGF2; TLE2; IRF1; SSBP3; RORA; HDAC9; BCL11A; SHOX2; MLXIP; IRF6; FOXN3; ELF3; VPS72; ID2; HMGA1; ZNF580; ZNF184; POU2AF1; TAL1; PBX1; INSM1; FLI1; MED24; STAT4; TFAP2C; HEY2; SOX11; HOXB2; HOXA5; YBX3; KLF2; KLF5; SOX9; EMX2; SATB2; NR2F1; MAFB; NCOR2; SPDEF; MYRF; ZIC1; BCL3; HTATIP2; ZNF589; BACH2; KLF4; TRIP6; PSIP1; MEIS2; IKZF1; MEF2C; ABL1
Down-regulation 45 NFKBIA; XBP1; PAX8; TFDP1; CCNA2; HNRNPD; ETS1; CCNH; SFPQ; GMNN; GATAD2A; NFIL3; SIX1; MEOX1; TAF9; CCNC; USP22; WWC1; ENO1; HSBP1; PSMC3IP; PEG3; ATF1; SIM2; YWHAB; ZBTB38; IRF4; CBFB; ZBED2; MYBL1; RUNX1; TSC22D2; NFATC3; LMCD1; CREB3L2; HMGN3; CALR; MTF2; FLNA; HOXC6; CREB1; BBX; WT1; ESR1; THAP11