Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08194 Gsk-2126458 GSE70138 HA1E Human 24h 1.11uM EID0010
Types Number Response transcription factors
Up-regulation 151 ZNF33B; ZNF195; FOXO4; MED12; HBP1; SOX4; TCEA2; EZH1; HDAC5; PIAS4; ING4; THRA; NPAS2; TCEA1; CBX7; PRDM2; POU2AF1; NONO; CEBPD; SUPT6H; CIR1; ZNF223; ZNF117; TRIB3; PRMT2; ZNF74; FOXM1; DLX4; CBFA2T2; ZNF232; PBXIP1; DLX5; CALCOCO1; PCGF3; ZNF219; ZNF623; FEZF2; ZNF816; THAP10; KLF13; TSG101; POU5F1B; ZBTB17; SETDB1; ZNF536; DEAF1; AES; TDP2; NR2C1; TAL1; HMGA2; PHIP; ZNF345; PNRC1; ZNF500; CEBPZ; ZNF112; ZNF423; KLF3; ZZZ3; GTF2F1; BAZ2B; ETV4; HDAC9; TULP4; APEX1; INSR; TSC22D1; ACTL6B; HIC2; ZNF415; HOXB2; HIPK2; RNF141; LYL1; ZSCAN18; HOXD1; ID1; SOX13; HOXB13; DDX17; ZNF226; SALL2; ARNT2; RAD21; CREBL2; KMT2A; MTA1; SIX3; ZFHX3; SSBP3; NR1H4; HMGA1; ZBED1; ZNF32; TCF7; TLE2; FOXG1; CEBPB; JUP; PAX6; ST18; ELF3; DLX2; BRD8; SOX17; FOXN3; COPS2; CERS4; NANOG; TFCP2; ZNF302; KLF11; HEY1; TERF1; VGLL4; TGIF1; NKX2-2; ATN1; ZNF589; ETS2; NCOA2; BCL11A; TFAP2C; NR0B1; ZFP36L2; SOX11; KLF2; ZFP36L1; ID3; INSM1; MYRF; HEY2; GATA2; TLE4; HOXA5; KAT6B; ZHX2; PAX5; MAFB; FOXF2; BTG1; CTNNB1; TRIM22; TBX3; PBX3; SPDEF; CTBP2; YBX3; MEIS1; MEF2C
Down-regulation 68 NFKBIA; MYCBP; PAX8; CCNA2; XBP1; BHLHE40; PIAS2; ATF6; GTF2A2; NUP62; IRF4; NFIL3; PTRF; ELF5; SIX1; VEZF1; GATAD2A; KDM2A; DR1; YWHAB; WWC1; MBD2; BAZ1A; LMCD1; EGR1; ENO1; IRX5; ZNF652; TEAD1; HOXC10; STAT3; CRY1; BATF; CCNC; MTDH; TRIM16; NFKB1; JARID2; RUNX1; ZEB2; SIAH2; HLTF; SFPQ; PDLIM1; MED1; CREB3L2; PURA; MAGED1; IL16; RUNX3; MEOX1; SUB1; RNF6; NFATC3; PEG3; TSC22D2; TRIM29; NR2F2; BCL3; LITAF; EHF; ZBTB18; ZBTB38; MYCN; PITX1; FOXC1; TOX3; TOB1