Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08192 Gsk-2126458 GSE70138 HA1E Human 24h 10uM EID0010
Types Number Response transcription factors
Up-regulation 176 SOX4; HBP1; EZH1; HES1; FOXO4; HDAC5; TSC22D3; TCEA2; NEUROD6; DDIT3; ZNF688; ATF4; PRDM2; ZNF500; MZF1; SETDB1; PSMD9; ING4; CEBPB; SSBP3; HSF4; CALCOCO1; CAMTA2; HMGA2; ZNF117; ZNF358; ZNF33B; THRA; ZNF219; HOXB13; FEZF2; NPAS2; CBFA2T2; TAF6; SNAPC4; ZMIZ2; CBX7; GTF2IRD1; HOXD1; AES; CRTC1; TLE2; ZNF74; LZTR1; USP21; KDM5B; SIN3B; ZBTB17; MED13; HDAC4; PCGF1; PPARD; ZBTB48; ZNF195; KLF13; RORA; HDAC11; MAFB; MTA1; DLX4; HINFP; ZNF202; PBXIP1; RHOA; NLK; BRPF1; TBX19; SIX6; ZNF232; INSR; TULP4; ZIC3; KMT2B; MEN1; BRD3; LHX3; SIRT7; USF2; PAX6; NONO; CNOT2; FOXG1; ATOH1; KLF3; NFATC1; ZNF532; LDB1; EN1; BCL11A; PNRC1; FOXA2; APEX1; BAZ2B; HMG20B; RXRA; ZNF282; TGIF1; TADA3; CEBPG; TFDP2; SIX3; BARX1; NR2E1; ZNF133; CBX6; MLXIP; MED15; JUND; ARNT2; SUPT3H; MXI1; CERS4; TFEB; CXXC1; NR0B1; EHMT2; CAPN15; BAZ1B; HMGA1; DDX17; TDP2; ZNF43; KLF7; TRIB3; STAT6; ARNTL; SALL2; SRCAP; PIAS1; CERS6; FOXN3; DBP; LYL1; MED24; HIRA; SATB2; ZHX2; TWIST1; MAFG; JUP; MEOX2; BRD4; FOXA1; DLX5; SMAD7; ZNF91; TSC22D1; CUX1; SOX11; BTG1; HOXA5; NR1H2; ERBB4; BACH2; RBFOX2; FOXF2; HLF; YBX3; MYRF; SPEN; BCL3; ZFP36L1; IRF6; NKX2-2; ZIC1; STAT4; ST18; CTNNB1; TBX3; PITX1; TBL1X; AEBP1; INSM1; TRIM22; ABL1; CREB1
Down-regulation 96 LOXL2; MYCBP; ATF6; XBP1; PAX8; MYBL2; PARP1; FHL2; TFDP1; DR1; PTRF; SUV39H1; CCNA2; EED; SMARCA5; NUP62; HNRNPD; WDR77; PPRC1; CCNC; NPAT; MEOX1; WWC1; STAT3; PIR; MTDH; ENO1; PEG3; TEAD1; SFPQ; PSMC3; HOXC10; ATF1; ZNF652; CCNH; ARID5B; ZBTB38; ZNF14; CRY1; CBX3; ETS1; YWHAB; ANKRD1; LMCD1; HSBP1; MBD2; ZNF512B; ZBTB11; TAF9B; ZNF593; CTR9; RUNX1; TMF1; RBBP7; TRIM29; DACH1; TSC22D2; MAGED1; CBFB; MYBL1; RAN; IRF4; BMI1; C1QBP; ZNF468; EHF; ELF5; BIRC2; TAF1D; E2F3; MECOM; WT1; BAZ1A; RBBP8; HOXB6; SUB1; BHLHE41; HLTF; NFATC3; MITF; PQBP1; BBX; LEF1; CREB3L2; FLNA; EGR3; NR4A1; HOXC6; ID4; TOB1; ZBTB18; SNAI2; ATF3; NR2F2; ID3; ESR1