Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08178	Azd-7762	GSE70138	HA1E	Human	24h	0.37uM	EID0010

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	NFATC4; NFKBIA; EGR1; TCEA2; NFKB2; IRF1; IRF9; MAFF; ATF4; ZNF211; SMARCD2; CREM; CEBPD; HES1; HMG20B; CREG1; BRD2; SUPT4H1; WNT4; ZNF45; NKX2-5; STAT1; RSF1; NFKBIB; SIX6; STAT2; KLF10; DBP; BCL3; ERF; ZNF264; NR1H4; NAB2; ZMIZ2; CBX7; EZH2; NR4A3; SRCAP; SLC2A4RG; ZBTB43; ATF3; BAZ1B; PLAG1; NR2E1; CBX6; SSX1; BRF2; IRF7; CALCOCO1; ID2; ZNF267; IRF5; SRF; TRIM22; TFEB; MEIS2; TP63; HOXA11; HOXC10; PBXIP1; RUNX3; SREBF1; CERS4; OSR2; DDIT3; PBX1; HOXD11; POU4F1; TEAD3; CEBPB; GATA1; HDGF; EMX2; PLAGL1; SAP18; TWIST1; FOXO1; ATF7IP; JUNB; AR; IRF8; IFI16; IKBKAP; RXRA; BHLHE41; SP110; PITX1; IRF6; YBX3; ELF3; KLF4; FOXG1; HOXB2; ZNF91; CRYM; KDM5D; MYRF; TRIP6; MSX1; SOX9; SATB2; NR1H2; LEF1; RELB; SOX11
Down-regulation	68	ZMIZ1; USP22; HSBP1; PRKDC; STAT5B; SOX4; TFDP1; ERG; TULP4; TBL1XR1; CCNC; CCNH; NPAT; ETS2; KLF2; HIF1A; CNBP; RNF111; SUPT3H; C1D; SFPQ; FUBP1; SMARCC1; PFDN5; SMAD4; BRCA1; DEK; ETS1; ZNF593; RCOR3; CBFB; APEX1; JARID2; C1QBP; NRIP1; AGO2; TGIF2; FOXJ3; ATF1; HMBOX1; BANP; MYCN; NPM1; ENO1; ASCL1; DMTF1; ZBTB18; NR2F2; AFF1; HHEX; FOXN3; ZNF165; PHF20; ZNF512B; THAP11; MNAT1; NFIB; MAGED1; ELK3; TGFB1; HOXA5; KAT6B; BBX; ZEB1; AHR; SNAI2; CREB1; ETV1