Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08176 Azd-7762 GSE70138 HA1E Human 24h 3.33uM EID0010
Types Number Response transcription factors
Up-regulation 223 CEBPD; NFKBIA; PRDM14; ATF3; JUP; ZNF195; PIAS4; CEBPB; HDAC5; SALL2; ZNF33B; TRIB3; ZNF75D; CBFA2T3; BCL11A; ZNF688; ZNF606; HOXD1; HDAC9; FOXO4; ZNF695; ZNF331; CD3D; ARNT2; ZNF544; ZNF219; MYCL; ZNF180; INSR; CBX7; ZNF264; SPI1; TP73; ZBTB48; NR5A2; ST18; ZNF223; ZNF235; IRF9; SOX17; IRF6; NR1H4; TAF5; FOXM1; ZNF232; TFAP2A; LHX3; PRDM10; SOX13; TCEA2; IRF3; ZNF816; TBX1; E2F4; CBFA2T2; NKX3-2; FEZF2; ZNF682; ZFPM2; THAP10; DLX4; MAK; ZIC3; ATOH1; ZNF345; THRB; RARG; THRA; ING4; CBX4; ZNF573; NR5A1; ZNF215; ZSCAN9; ZNF771; NFIX; AR; SOX5; NR4A2; ZFHX3; TFAP2C; THAP7; SSBP3; SIX6; PRDM2; CERS4; FOXA1; GBX1; OVOL2; ZNF3; ESRRA; ZNF423; CDIP1; ESRRG; HOXB1; ZNF623; ACTL6B; TULP3; SPDEF; BRD4; ZNF467; TCF7L2; NKX3-1; HOXB2; SIX3; LDB1; CREG1; KLF15; MEIS2; E2F8; CNOT3; SOX18; CRYM; HINFP; ZNF175; TSC22D1; NPAS2; NLK; IRF1; ZNF304; NR4A1; FOXF2; JUND; GRHL2; VPS72; CREBL2; SMARCB1; NEUROD1; HIPK2; EN1; SOX3; BARX1; ZNF112; PBXIP1; ZNF10; ATN1; PAX6; EMX2; IRX4; ZNF536; ZNF239; ZNF415; PNRC1; SOHLH2; ELF3; TP63; CHD4; HHEX; MDM2; TAL1; ID1; SCAND1; IRF8; MYB; DLX5; PHIP; NANOG; WNT4; NR2E1; RING1; ERBB4; BCL6; ZFP36L2; OSR2; ZHX2; KLF11; HOXB13; KDM5D; EHF; TDP2; AES; BAZ2B; POU2AF1; STAT4; MEOX2; ARID1A; TOX; SALL1; CUX2; ZNF611; TRIM24; CAMTA1; SHOX2; MNDA; CEBPA; LYL1; RFX5; ZBED1; FOXN3; ETS2; HEY1; TFEC; EYA2; INSM1; HLF; RBPMS; KLF4; ISL1; TCF21; LIN28A; PIR; FOXF1; ZBED2; ZNF589; YBX3; TRIM29; SOX11; STAT1; LITAF; KLF5; NFE2L3; PITX1; TRIM22; TOB1; NR1H2; PBX1; CITED2; DACH1; ESR1; MEF2C; SOX2; MEIS1; RELB
Down-regulation 101 ECD; ATF6; FOSL1; RHOA; TCERG1; MAGED1; FOXO3; REST; HNRNPD; ENO1; BHLHE40; MBD2; CCNA2; EED; IRF4; BMI1; ZBTB38; ADNP; DNAJC2; TRIM32; SMAD2; JARID2; NUP62; ZEB2; CRY1; ATF1; TSC22D2; NR1D2; BCLAF1; NPM1; YWHAB; HSBP1; PURA; ZBTB1; MED1; RNF14; ZMIZ1; KLF6; UBE2I; BATF; XBP1; ELK3; SMARCE1; ZMYND11; VEZF1; TBL1XR1; IKZF5; ETS1; TAF9; IRX5; TCFL5; CBFB; ING2; YAF2; CREB3L1; RAN; NCOA6; NCOA4; EDF1; AFF1; FLNA; MTDH; HIPK3; RNF111; CBX3; SFPQ; RARA; FOXC1; CCNC; SMAD7; RBBP4; NRIP1; BATF3; NEDD8; RCOR1; PTRF; NCOA1; DNAJC1; RBM14; FOXD1; BASP1; CHD1; NR2F6; EGR2; SAP30; HOXC6; NCOR2; NRBF2; NR2F2; HLTF; MNAT1; MYBL1; CHD7; VGLL4; MXI1; HOXA5; HOXC10; NFATC3; BBX; ZBTB18; MSX1